HitPredict

Interactor 1: MLP3C (Q9BXW4)
Microtubule-associated protein 1 light chain 3 gamma (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (Microtubule-associated proteins 1A/1B light chain 3C) (MAP1A/MAP1B LC3 C) (MAP1A/MAP1B light chain 3 C)
Gene: MAP1LC3C

Interactor 2: UBA5 (Q9GZZ9)
Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (ThiFP1) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1)
Gene: UBA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.681

Property	Details
Experiments	20562859
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ATG8~ThiF
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 404
+	Hs
		328145 GBRAP_HUMAN (13-127): 3.46e-54: 168: 38.26		UBA5_HUMAN (1-404): 1.81e-151: 436: 100.00
+	Hs
		952335 GBRL2_HUMAN (13-126): 1.66e-54: 168: 42.98		UBA5_HUMAN (1-404): 1.81e-151: 436: 100.00
+	Hs
		1428343 MLP3B_HUMAN (7-127): 8.19e-53: 164: 54.55		UBA5_HUMAN (1-404): 1.81e-151: 436: 100.00
+	Sc
		795332 ATG8_YEAST (11-126): 1.29e-54: 169: 38.79		UBA4_YEAST (9-337): 9.81e-91: 282: 18.13
+	Sc
		795335 ATG8_YEAST (11-126): 1.29e-54: 169: 38.79		ATG7_YEAST (39-351): 1.12e-80: 261: 15.76
+	Hs
		334234 MLP3C_HUMAN (1-147): 4.66e-72: 214: 100.00		ATG7_HUMAN (19-351): 3.69e-60: 208: 13.69
+	At
		1376074 ATG8D_ARATH (9-128): 7.61e-61: 185: 41.67		ATG7_ARATH (24-350): 2.99e-60: 208: 13.94
+	At
		1354489 ATG8F_ARATH (9-126): 2.15e-58: 178: 42.37		ATG7_ARATH (24-350): 2.99e-60: 208: 13.94
+	Dm
		1263327 Q9W2S2_DROME (13-127): 6.16e-55: 170: 37.39		Q7JY94_DROME (39-320): 1.62e-61: 212: 15.74
+	Dm
		57962 Q9W2S2_DROME (13-127): 6.16e-55: 170: 37.39		A1ZBA9_DROME (39-320): 6.3e-63: 212: 15.74
+	Hs
		327708 GBRAP_HUMAN (13-127): 3.46e-54: 168: 38.26		ATG7_HUMAN (19-351): 3.69e-60: 208: 13.69
+	Hs
		334166 GBRL2_HUMAN (13-126): 1.66e-54: 168: 42.98		ATG7_HUMAN (19-351): 3.69e-60: 208: 13.69
+	Mm
		1424167 GBRAP_MOUSE (13-127): 3.46e-54: 168: 38.26		ATG7_MOUSE (19-351): 2.51e-59: 206: 13.97
+	Mm
		952401 GBRL2_MOUSE (13-126): 1.66e-54: 168: 42.98		ATG7_MOUSE (19-351): 2.51e-59: 206: 13.97
+	Hs
		334242 MLP3A_HUMAN (7-126): 2.5e-53: 165: 59.17		ATG7_HUMAN (19-351): 3.69e-60: 208: 13.69
+	Hs
		334239 MLP3B_HUMAN (7-127): 8.19e-53: 164: 54.55		ATG7_HUMAN (19-351): 3.69e-60: 208: 13.69
+	Mm
		1362239 MLP3A_MOUSE (7-126): 2.5e-53: 165: 59.17		ATG7_MOUSE (19-351): 2.51e-59: 206: 13.97
+	Mm
		1423747 MLP3B_MOUSE (7-126): 6.51e-53: 165: 55.00		ATG7_MOUSE (19-351): 2.51e-59: 206: 13.97
+	Ce
		109695 LGG1_CAEEL (12-126): 1.47e-52: 164: 38.26		G5EBK4_CAEEL (43-279): 1.68e-53: 190: 15.47
+	Sc
		649488 ATG8_YEAST (11-126): 1.29e-54: 169: 38.79		UBA1_YEAST (44-218): 2.66e-27: 116: 19.21