HitPredict

Interactor 1: GBRAP (O95166)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46)
Gene: GABARAP

Interactor 2: UBA5 (Q9GZZ9)
Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (ThiFP1) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1)
Gene: UBA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.681

Property	Details
Experiments	20562859
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ATG8~ThiF
Common GO terms	GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 117 Hs			1 404
+	Hs
		952335 GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27		UBA5_HUMAN (1-404): 1.81e-151: 436: 100.00
+	Hs
		1429200 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		UBA5_HUMAN (1-404): 1.81e-151: 436: 100.00
+	Hs
		1417410 MLP3C_HUMAN (5-116): 1.16e-44: 143: 38.60		UBA5_HUMAN (1-404): 1.81e-151: 436: 100.00
+	Sc
		795332 ATG8_YEAST (1-116): 9.22e-59: 178: 55.17		UBA4_YEAST (9-337): 9.81e-91: 282: 18.13
+	Sc
		795335 ATG8_YEAST (1-116): 9.22e-59: 178: 55.17		ATG7_YEAST (39-351): 1.12e-80: 261: 15.76
+	At
		1376074 ATG8D_ARATH (3-117): 3.42e-62: 186: 56.52		ATG7_ARATH (24-350): 2.99e-60: 208: 13.94
+	At
		1354489 ATG8F_ARATH (2-117): 1.06e-61: 185: 58.62		ATG7_ARATH (24-350): 2.99e-60: 208: 13.94
+	Dm
		1263327 Q9W2S2_DROME (1-117): 5.31e-58: 176: 91.45		Q7JY94_DROME (39-320): 1.62e-61: 212: 15.74
+	Dm
		57962 Q9W2S2_DROME (1-117): 5.31e-58: 176: 91.45		A1ZBA9_DROME (39-320): 6.3e-63: 212: 15.74
+	Hs
		334166 GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27		ATG7_HUMAN (19-351): 3.69e-60: 208: 13.69
+	Mm
		952401 GBRL2_MOUSE (1-117): 2.76e-58: 176: 57.27		ATG7_MOUSE (19-351): 2.51e-59: 206: 13.97
+	Hs
		327708 GBRAP_HUMAN (1-117): 8.09e-57: 173: 100.00		ATG7_HUMAN (19-351): 3.69e-60: 208: 13.69
+	Mm
		1424167 GBRAP_MOUSE (1-117): 8.09e-57: 173: 100.00		ATG7_MOUSE (19-351): 2.51e-59: 206: 13.97
+	Hs
		334240 GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07		ATG7_HUMAN (19-351): 3.69e-60: 208: 13.69
+	Ce
		109695 LGG1_CAEEL (1-116): 2.48e-55: 170: 83.62		G5EBK4_CAEEL (43-279): 1.68e-53: 190: 15.47
+	Hs
		334242 MLP3A_HUMAN (5-117): 2.3e-45: 144: 30.44		ATG7_HUMAN (19-351): 3.69e-60: 208: 13.69
+	Hs
		334234 MLP3C_HUMAN (5-116): 1.16e-44: 143: 38.60		ATG7_HUMAN (19-351): 3.69e-60: 208: 13.69
+	Mm
		1362239 MLP3A_MOUSE (5-117): 2.3e-45: 144: 30.44		ATG7_MOUSE (19-351): 2.51e-59: 206: 13.97
+	Mm
		1423747 MLP3B_MOUSE (2-116): 2.1e-44: 142: 30.77		ATG7_MOUSE (19-351): 2.51e-59: 206: 13.97
+	Sc
		649488 ATG8_YEAST (1-116): 9.22e-59: 178: 55.17		UBA1_YEAST (44-218): 2.66e-27: 116: 19.21