HitPredict

Interactor 1: QRIC2 (Q9H0J4)
Glutamine-rich protein 2
Gene: QRICH2

Interactor 2: KMT2B (Q9UMN6)
Histone-lysine N-methyltransferase 2B (Lysine N-methyltransferase 2B) (EC 2.1.1.364) (Myeloid/lymphoid or mixed-lineage leukemia protein 4) (Trithorax homolog 2) (WW domain-binding protein 7) (WBP-7)
Gene: KMT2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	23995757
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1663 Hs			1 2715
+	Hs
		1338285 KMT2C_HUMAN (20-949): 1.09e-27: 125: 9.49		KMT2B_HUMAN (1-2715): 0: 1031: 100.00
+	Hs
		1130608 NCOA6_HUMAN (480-1031): 5.78e-11: 70.1: 8.88		KMT2B_HUMAN (1-2715): 0: 1031: 100.00
+	Hs
		590286 MUC1_HUMAN (160-1077): 1.64e-44: 179: 10.17		EZH2_HUMAN (2250-2697): 7.01e-67: 245: 16.51
+	Hs
		1338286 KMT2C_HUMAN (20-949): 1.09e-27: 125: 9.49		SET1B_HUMAN (1961-2715): 1.85e-66: 253: 23.84
+	Hs
		1155848 RRBP1_HUMAN (350-914): 5.18e-30: 132: 17.35		EZH2_HUMAN (2250-2697): 7.01e-67: 245: 16.51
+	Hs
		1155553 KMT2C_HUMAN (20-949): 1.09e-27: 125: 9.49		EZH2_HUMAN (2250-2697): 7.01e-67: 245: 16.51
+	Hs
		1155846 CHD7_HUMAN (71-607): 9.36e-21: 102: 12.98		EZH2_HUMAN (2250-2697): 7.01e-67: 245: 16.51
+	Hs
		1041559 KMT2C_HUMAN (20-949): 1.09e-27: 125: 9.49		KMT2A_HUMAN (1780-2715): 1.77e-52: 207: 29.82
+	Hs
		1130610 NCOA6_HUMAN (480-1031): 5.78e-11: 70.1: 8.88		SET1B_HUMAN (1961-2715): 1.85e-66: 253: 23.84
+	Hs
		161476 KMT2D_HUMAN (174-1016): 5.14e-09: 63.8: 10.02		EZH2_HUMAN (2250-2697): 7.01e-67: 245: 16.51
+	Hs
		1041523 NCOA6_HUMAN (480-1031): 5.78e-11: 70.1: 8.88		KMT2A_HUMAN (1780-2715): 1.77e-52: 207: 29.82
+	Hs
		161451 KMT2D_HUMAN (174-1016): 5.14e-09: 63.8: 10.02		KMT2A_HUMAN (1780-2715): 1.77e-52: 207: 29.82
+	Hs
		175910 KMT2C_HUMAN (20-949): 1.09e-27: 125: 9.49		SET1A_HUMAN (2571-2715): 1.53e-26: 122: 52.74
+	Hs
		161491 KMT2C_HUMAN (20-949): 1.09e-27: 125: 9.49		KMT2D_HUMAN (396-778): 8.81e-10: 67.2: 20.80
+	Hs
		161371 KMT2D_HUMAN (174-1016): 5.14e-09: 63.8: 10.02		SET1A_HUMAN (2571-2715): 1.53e-26: 122: 52.74
+	Dm
		119660 M9PB30_DROME (26-773): 1.34e-12: 75.5: 9.03		M9PB30_DROME (802-1163): 6.5e-14: 80.9: 13.56
+	Mm
		1455913 PCLO_MOUSE (595-1091): 9.33e-10: 66.2: 8.20		PCLO_MOUSE (1776-2411): 2.01e-12: 75.9: 10.79
+	Hs
		161467 NCOA6_HUMAN (480-1031): 5.78e-11: 70.1: 8.88		KMT2D_HUMAN (396-778): 8.81e-10: 67.2: 20.80
+	Mm
		1297309 NCOA6_MOUSE (139-1088): 8.19e-12: 72.8: 7.66		KMT2C_MOUSE (1780-2314): 6.97e-09: 64: 14.34
+	Hs
		1130579 NCOA6_HUMAN (480-1031): 5.78e-11: 70.1: 8.88		KMT2C_HUMAN (2005-2475): 3.88e-09: 65.1: 11.39