HitPredict

Interactor 1: P2Y12 (Q9H244)
P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999)
Gene: P2RY12

Interactor 2: TNPO3 (Q9Y5L0)
Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR)
Gene: TNPO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 342 Hs			1 923
+	Hs
		1101716 GPR17_HUMAN (7-333): 1.74e-71: 228: 24.70		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		833891 P2RY2_HUMAN (17-304): 7.37e-71: 227: 24.22		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		173268 LPAR4_HUMAN (7-309): 2.53e-89: 274: 26.56		XPO1_HUMAN (3-920): 6.79e-151: 475: 12.37
+	Hs
		172773 GPR17_HUMAN (7-333): 1.74e-71: 228: 24.70		XPO1_HUMAN (3-920): 6.79e-151: 475: 12.37
+	Hs
		172836 P2RY6_HUMAN (1-325): 8.32e-69: 220: 21.04		XPO1_HUMAN (3-920): 6.79e-151: 475: 12.37
+	Hs
		318134 GPR17_HUMAN (7-333): 1.74e-71: 228: 24.70		IPO13_HUMAN (5-923): 2.11e-143: 452: 21.02
+	Hs
		318135 P2RY6_HUMAN (1-325): 8.32e-69: 220: 21.04		IPO13_HUMAN (5-923): 2.11e-143: 452: 21.02
+	Hs
		164546 LPAR6_HUMAN (13-335): 8.77e-88: 269: 25.69		TNPO2_HUMAN (68-784): 3.35e-92: 313: 12.26
+	Hs
		334778 P2RY6_HUMAN (1-325): 8.32e-69: 220: 21.04		IPO7_HUMAN (13-813): 8.67e-101: 340: 11.63
+	Hs
		220905 GPR17_HUMAN (7-333): 1.74e-71: 228: 24.70		XPOT_HUMAN (12-770): 1.77e-93: 318: 15.10
+	Hs
		164568 GPR17_HUMAN (7-333): 1.74e-71: 228: 24.70		TNPO2_HUMAN (68-784): 3.35e-92: 313: 12.26
+	Hs
		220911 P2RY6_HUMAN (1-325): 8.32e-69: 220: 21.04		XPOT_HUMAN (12-770): 1.77e-93: 318: 15.10
+	Hs
		1142125 P2RY6_HUMAN (1-325): 8.32e-69: 220: 21.04		TNPO1_HUMAN (66-784): 4.01e-93: 316: 12.71
+	Hs
		189155 GPR17_HUMAN (7-333): 1.74e-71: 228: 24.70		IPO8_HUMAN (10-813): 5.23e-89: 307: 9.92
+	Hs
		189122 P2RY2_HUMAN (17-304): 7.37e-71: 227: 24.22		IPO8_HUMAN (10-813): 5.23e-89: 307: 9.92
+	Hs
		189166 P2RY6_HUMAN (1-325): 8.32e-69: 220: 21.04		IPO8_HUMAN (10-813): 5.23e-89: 307: 9.92
+	Hs
		134039 P2RY6_HUMAN (1-325): 8.32e-69: 220: 21.04		IPO5_HUMAN (68-703): 1.93e-86: 301: 13.24
+	Hs
		1101666 GPR17_HUMAN (7-333): 1.74e-71: 228: 24.70		XPO5_HUMAN (9-614): 3.05e-22: 105: 14.21
+	Hs
		1142183 P2RY6_HUMAN (1-325): 8.32e-69: 220: 21.04		XPO5_HUMAN (9-614): 3.05e-22: 105: 14.21
+	Hs
		1134206 P2RY6_HUMAN (1-325): 8.32e-69: 220: 21.04		IMB1_HUMAN (38-691): 1.58e-09: 64.1: 9.56