Interactor 1: TRXR2 (Q9JLT4)
Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Thioredoxin reductase TR3)
Gene: Txnrd2

Interactor 2: TRXR2 (Q9JLT4)
Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Thioredoxin reductase TR3)
Gene: Txnrd2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 29199018, 29222160
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pyr_redox_2~Pyr_redox_2, Pyr_redox_2~Pyr_redox_dim, Pyr_redox_dim~Pyr_redox_dim
Common GO terms GO:0000305 - response to oxygen radical
GO:0004791 - thioredoxin-disulfide reductase (NADPH) activity
GO:0005739 - mitochondrion
GO:0007507 - heart development
GO:0030097 - hemopoiesis
and 3 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 524
Mm

1 524
+ Hs
+ Hs
+ Rn
+ Hs
+ Dm
+ Dm
+ Hs
+ Mm
+ At
+ Sp
+ Sc
+ Ec
+ Sc
+ Ec
+ Mp
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025