HitPredict

Interactor 1: DLDH (P09622)
Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)
Gene: DLD

Interactor 2: DLDH (P09622)
Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)
Gene: DLD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pyr_redox_2~Pyr_redox_2, Pyr_redox_2~Pyr_redox_dim, Pyr_redox_dim~Pyr_redox_dim
Common GO terms GO:0004148 - dihydrolipoyl dehydrogenase (NADH) activity
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006086 - pyruvate decarboxylation to acetyl-CoA
and 16 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 509
Hs

1 509
+ Mm
+ Dm
+ Mm
+ Dm
+ Hs
+ Sc
+ Hs
+ Rn
+ Hs
+ At
+ Ec
+ Ec
+ Sp
+ Sc
+ Mp

Service provided by Combinatics, Japan

Last updated: 11Aug2025