HitPredict

Interactor 1: RAB6B (Q9NRW1)
Ras-related protein Rab-6B (EC 3.6.5.2)
Gene: RAB6B

Interactor 2: S12A4 (Q9UP95)
Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1)
Gene: SLC12A4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.587

Property	Details
Experiments	33961781, unassigned3799, unassigned3795
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Hs			1 1085
+	Hs
		1200383 RAB6D_HUMAN (1-208): 1.7e-96: 282: 82.69		S12A4_HUMAN (1-1085): 0: 1170: 100.00
+	Mm
		770514 RAB5C_MOUSE (3-207): 4.26e-89: 262: 40.98		S12A4_MOUSE (1-1085): 0: 1173: 96.22
+	Hs
		901107 RAB5C_HUMAN (3-207): 5.92e-89: 262: 40.98		S12A4_HUMAN (1-1085): 0: 1170: 100.00
+	Hs
		631564 RAB5A_HUMAN (3-207): 6.38e-89: 261: 40.78		S12A4_HUMAN (1-1085): 0: 1170: 100.00
+	Hs
		1200382 RAB6D_HUMAN (1-208): 1.7e-96: 282: 82.69		S12A6_HUMAN (7-1085): 0: 1100: 76.43
+	Hs
		901090 RAB5C_HUMAN (3-207): 5.92e-89: 262: 40.98		S12A6_HUMAN (7-1085): 0: 1100: 76.43
+	Hs
		631540 RAB5A_HUMAN (3-207): 6.38e-89: 261: 40.78		S12A6_HUMAN (7-1085): 0: 1100: 76.43
+	Hs
		1448885 RAB6B_HUMAN (1-208): 3.28e-86: 255: 100.00		S12A6_HUMAN (7-1085): 0: 1100: 76.43
+	Hs
		901121 RAB5C_HUMAN (3-207): 5.92e-89: 262: 40.98		S12A7_HUMAN (1-1085): 0: 1056: 69.05
+	Hs
		631598 RAB5A_HUMAN (3-207): 6.38e-89: 261: 40.78		S12A7_HUMAN (1-1085): 0: 1056: 69.05
+	Hs
		900744 RAB5C_HUMAN (3-207): 5.92e-89: 262: 40.98		S12A2_HUMAN (37-1085): 0: 744: 21.39
+	Hs
		631140 RAB5A_HUMAN (3-207): 6.38e-89: 261: 40.78		S12A2_HUMAN (37-1085): 0: 744: 21.39
+	Hs
		901018 RAB5C_HUMAN (3-207): 5.92e-89: 262: 40.98		S12A9_HUMAN (116-911): 6.02e-143: 454: 26.23
+	Hs
		981348 RAB1A_HUMAN (1-207): 1.17e-87: 258: 34.30		S12A9_HUMAN (116-911): 6.02e-143: 454: 26.23
+	Hs
		1417154 RAB6B_HUMAN (1-208): 3.28e-86: 255: 100.00		S12A9_HUMAN (116-911): 6.02e-143: 454: 26.23
+	Hs
		900737 RAB5C_HUMAN (3-207): 5.92e-89: 262: 40.98		CTR2_HUMAN (161-603): 3.4e-90: 305: 15.99
+	Hs
		631135 RAB5A_HUMAN (3-207): 6.38e-89: 261: 40.78		CTR2_HUMAN (161-603): 3.4e-90: 305: 15.99
+	Hs
		722419 RAB5C_HUMAN (3-207): 5.92e-89: 262: 40.98		CTR1_HUMAN (162-603): 9.04e-82: 281: 13.06
+	Hs
		900778 RAB5C_HUMAN (3-207): 5.92e-89: 262: 40.98		LAT1_HUMAN (162-687): 2.34e-77: 265: 13.65
+	Hs
		631171 RAB5A_HUMAN (3-207): 6.38e-89: 261: 40.78		LAT1_HUMAN (162-687): 2.34e-77: 265: 13.65