HitPredict

Interactor 1: NRBP2 (Q9NSY0)
Nuclear receptor-binding protein 2 (Transformation-related gene 16 protein) (TRG-16)
Gene: NRBP2

Interactor 2: T22D4 (Q9Y3Q8)
TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2)
Gene: TSC22D4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.738

Property	Details
Experiments	25416956, 26186194, 28514442, 33961781, 32707033, unassigned3799
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 501 Hs			1 395
+	Hs
		1460142 NRBP_HUMAN (2-500): 5.35e-116: 353: 59.36		T22D4_HUMAN (1-395): 1.6e-61: 205: 100.00
+	Hs
		1418965 WNK3_HUMAN (29-451): 2.17e-105: 347: 25.11		T22D4_HUMAN (1-395): 1.6e-61: 205: 100.00
+	Hs
		1459053 STK39_HUMAN (34-491): 3.12e-112: 344: 15.08		T22D4_HUMAN (1-395): 1.6e-61: 205: 100.00
+	Hs
		1491265 WNK2_HUMAN (2-314): 1.23e-103: 342: 29.91		T22D4_HUMAN (1-395): 1.6e-61: 205: 100.00
+	Hs
		1152480 NRBP2_HUMAN (28-501): 3.63e-132: 394: 100.00		T22D1_HUMAN (28-394): 3.43e-36: 142: 26.01
+	Hs
		1433326 WNK1_HUMAN (5-433): 5.21e-97: 323: 24.42		T22D4_HUMAN (1-395): 1.6e-61: 205: 100.00
+	Hs
		1095488 AAPK1_HUMAN (37-448): 2.17e-98: 309: 16.03		T22D4_HUMAN (1-395): 1.6e-61: 205: 100.00
+	Hs
		273287 NRBP2_HUMAN (28-501): 3.63e-132: 394: 100.00		T22D2_HUMAN (23-392): 1.25e-26: 114: 27.39
+	Hs
		1308451 NRBP_HUMAN (2-500): 5.35e-116: 353: 59.36		Q8IV54_HUMAN (1-310): 1.44e-42: 153: 99.68
+	Hs
		1152490 NRBP_HUMAN (2-500): 5.35e-116: 353: 59.36		T22D1_HUMAN (28-394): 3.43e-36: 142: 26.01
+	Hs
		1405416 NRBP2_HUMAN (28-501): 3.63e-132: 394: 100.00		T22D3_HUMAN (276-395): 9.51e-25: 100: 49.59
+	Rn
		976798 AKT3_RAT (10-380): 3.28e-117: 355: 13.91		T22D1_RAT (28-394): 1.23e-34: 138: 26.79
+	Hs
		273292 NRBP_HUMAN (2-500): 5.35e-116: 353: 59.36		T22D2_HUMAN (23-392): 1.25e-26: 114: 27.39
+	Hs
		1152470 WNK1_HUMAN (5-433): 5.21e-97: 323: 24.42		T22D1_HUMAN (28-394): 3.43e-36: 142: 26.01
+	Hs
		273283 WNK3_HUMAN (29-451): 2.17e-105: 347: 25.11		T22D2_HUMAN (23-392): 1.25e-26: 114: 27.39
+	Hs
		273290 STK39_HUMAN (34-491): 3.12e-112: 344: 15.08		T22D2_HUMAN (23-392): 1.25e-26: 114: 27.39
+	Hs
		1405417 NRBP_HUMAN (2-500): 5.35e-116: 353: 59.36		T22D3_HUMAN (276-395): 9.51e-25: 100: 49.59
+	Dm
		1174464 NRBP_DROME (13-494): 1.11e-119: 366: 47.98		BUN2_DROME (139-394): 1e-10: 65.7: 26.14
+	Hs
		343623 OXSR1_HUMAN (23-501): 7.46e-116: 353: 14.87		TITIN_HUMAN (5-287): 1.6e-10: 65.3: 11.15