Protein: T22D2
TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4)

Gene: T22D2, TSC22D2
Organism: Homo sapiens
Interactions: 61
UniProt ID: O75157

Gene Ontology (top 5):
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0006970 - response to osmotic stress
GO:0045786 - negative regulation of cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

273297

T22D4
TSC22 domain family protein 4

4

16

High-throughput

0.892

High

273278

T22D3
TSC22 domain family protein 3

2

9

High-throughput

0.811

High

273292

NRBP
Nuclear receptor-binding protein

6

15

Small-scale

0.669

High

273268

F117B
Protein FAM117B

2

1

High-throughput

0.574

High

273279

MEP50
Methylosome protein WDR77

1

20

Small-scale

0.552

High

273264

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

1

High-throughput

0.489

High

273265

C1QL3
Complement C1q-like protein 3

1

5

High-throughput

0.489

High

273285

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

8

High-throughput

0.489

High

273287

NRBP2
Nuclear receptor-binding protein 2

1

18

High-throughput

0.489

High

273295

DYN3
Dynamin-3

1

2

High-throughput

0.489

High

273259

ZN143
Zinc finger protein 143

1

4

Small-scale

0.481

High

273267

ARID2
AT-rich interactive domain-containing protein 2

1

20

Small-scale

0.481

High

273280

ZN251
Zinc finger protein 251

1

1

Small-scale

0.481

High

155140

NRG2
Pro-neuregulin-2, membrane-bound isoform

1

3

High-throughput

0.470

High

134497

SAP18
Histone deacetylase complex subunit SAP18

1

0

Small-scale

0.460

High

273276

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

16

High-throughput

0.457

High

60851

C144A
Coiled-coil domain-containing protein 144A

1

13

Small-scale

0.439

High

67226

AN36A
Ankyrin repeat domain-containing protein 36A

1

8

Small-scale

0.439

High

165215

PSA7
Proteasome subunit alpha type-7

1

4

Small-scale

0.439

High

249538

SNX3
Sorting nexin-3

1

2

Small-scale

0.439

High

253465

ANM3
Protein arginine N-methyltransferase 3

1

9

Small-scale

0.439

High

273244

FLNB
Filamin-B

1

5

Small-scale

0.439

High

273245

MPDZ
Multiple PDZ domain protein

1

4

Small-scale

0.439

High

273246

SC31A
Protein transport protein Sec31A

1

20

Small-scale

0.439

High

273248

FA8
Coagulation factor VIII

1

1

Small-scale

0.439

High

273250

LIPL
Lipoprotein lipase

1

1

Small-scale

0.439

High

273254

ITA2
Integrin alpha-2

1

4

Small-scale

0.439

High

273255

MSH3
DNA mismatch repair protein Msh3

1

1

Small-scale

0.439

High

273256

RBL1
Retinoblastoma-like protein 1

1

7

Small-scale

0.439

High

273257

CLIP1
CAP-Gly domain-containing linker protein 1

1

12

Small-scale

0.439

High

273269

CC141
Coiled-coil domain-containing protein 141

1

10

Small-scale

0.439

High

273271

DAA11
Dynein axonemal assembly factor 11

1

6

Small-scale

0.439

High

273272

LOXH1
Lipoxygenase homology domain-containing protein 1

1

1

Small-scale

0.439

High

273273

PSMA8
Proteasome subunit alpha-type 8

1

4

Small-scale

0.439

High

273275

TITIN
Titin

1

8

Small-scale

0.439

High

273277

RING2
E3 ubiquitin-protein ligase RING2

1

20

Small-scale

0.439

High

273282

OSBL1
Oxysterol-binding protein-related protein 1

1

2

Small-scale

0.439

High

273283

WNK3
Serine/threonine-protein kinase WNK3

1

16

Small-scale

0.439

High

273288

ZMYM2
Zinc finger MYM-type protein 2

1

3

Small-scale

0.439

High

273290

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

2

Small-scale

0.439

High

273291

MED13
Mediator of RNA polymerase II transcription subunit 13

1

1

Small-scale

0.439

High

273294

APC10
Anaphase-promoting complex subunit 10

1

9

Small-scale

0.439

High

273251

H14
Histone H1.4

1

6

High-throughput

0.437

High

273252

BIP
Endoplasmic reticulum chaperone BiP

1

10

High-throughput

0.437

High

273261

KEAP1
Kelch-like ECH-associated protein 1

1

8

Small-scale

0.437

High

273262

ELOB
Elongin-B

1

3

High-throughput

0.437

High

273263

ZYX
Zyxin

1

3

High-throughput

0.437

High

273266

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.407

High

273274

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

273247

SCEL
Sciellin

1

0

Small-scale

0.251

Low

273249

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

Small-scale

0.251

Low

273253

EPCAM
Epithelial cell adhesion molecule

1

0

Small-scale

0.251

Low

273258

IF2M
Translation initiation factor IF-2, mitochondrial

1

0

Small-scale

0.251

Low

273260

UFM1
Ubiquitin-fold modifier 1

1

0

Small-scale

0.251

Low

273270

GPBP1
Vasculin

1

0

Small-scale

0.251

Low

273281

TALD3
Protein TALPID3

1

0

Small-scale

0.251

Low

273284

SPEF2
Sperm flagellar protein 2

1

0

Small-scale

0.251

Low

273286

NGRN
Neugrin

1

0

Small-scale

0.251

Low

273289

REV1
DNA repair protein REV1

1

0

Small-scale

0.251

Low

273293

ENOPH
Enolase-phosphatase E1

1

0

Small-scale

0.251

Low

273296

TMA7
Translation machinery-associated protein 7

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025