Protein: SPSB2
SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9)

Gene: SPSB2
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q99619

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
GO:0035556 - intracellular signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1274026

CUL5
Cullin-5

5

20

Small-scale

0.927

High

1072293

ELOC
Elongin-C

4

6

Small-scale

0.910

High

1267424

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

10

High-throughput

0.819

High

718529

NOS2
Nitric oxide synthase, inducible

6

7

Small-scale

0.741

High

665651

EPHB2
Ephrin type-B receptor 2

3

12

High-throughput

0.667

High

1072433

ELOB
Elongin-B

3

4

Small-scale

0.667

High

1305045

TTC1
Tetratricopeptide repeat protein 1

3

14

High-throughput

0.667

High

164148

ARHGA
Rho guanine nucleotide exchange factor 10

3

18

High-throughput

0.656

High

1305212

RBX2
RING-box protein 2

2

7

Small-scale

0.628

High

1294769

PAWR
PRKC apoptosis WT1 regulator protein

2

4

Small-scale

0.619

High

1217271

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

1

19

High-throughput

0.618

High

1043182

CUL4A
Cullin-4A

1

20

High-throughput

0.618

High

1085279

NRF1
Nuclear respiratory factor 1

2

1

High-throughput

0.606

High

1305202

ANM1
Protein arginine N-methyltransferase 1

1

13

High-throughput

0.573

High

1120078

FND3B
Fibronectin type III domain-containing protein 3B

2

13

High-throughput

0.553

High

1292467

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

1

High-throughput

0.553

High

1282021

TRI63
E3 ubiquitin-protein ligase TRIM63

1

20

High-throughput

0.541

High

1305205

TRI55
Tripartite motif-containing protein 55

1

19

High-throughput

0.541

High

312651

ARI2
E3 ubiquitin-protein ligase ARIH2

1

15

High-throughput

0.536

High

850168

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

20

High-throughput

0.536

High

928444

DYL1
Dynein light chain 1, cytoplasmic

1

2

High-throughput

0.536

High

1056728

PUM1
Pumilio homolog 1

1

7

High-throughput

0.536

High

1251233

WDR48
WD repeat-containing protein 48

1

16

High-throughput

0.536

High

1292343

RN185
E3 ubiquitin-protein ligase RNF185

1

12

High-throughput

0.536

High

1305206

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

15

High-throughput

0.536

High

1305208

DOCK5
Dedicator of cytokinesis protein 5

1

10

High-throughput

0.536

High

1305211

FANCI
Fanconi anemia group I protein

1

2

High-throughput

0.536

High

228469

PRKN
E3 ubiquitin-protein ligase parkin

1

17

High-throughput

0.515

High

443750

VIME
Vimentin

1

10

High-throughput

0.515

High

896361

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

9

High-throughput

0.515

High

1305214

RNF11
RING finger protein 11

1

2

High-throughput

0.515

High

395565

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.501

High

1232537

GLT15
Polypeptide N-acetylgalactosaminyltransferase 15

1

6

High-throughput

0.494

High

299581

LRIG2
Leucine-rich repeats and immunoglobulin-like domains protein 2

1

10

High-throughput

0.489

High

438846

SRPRA
Signal recognition particle receptor subunit alpha

1

4

High-throughput

0.489

High

587366

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

8

High-throughput

0.489

High

592822

NR1D1
Nuclear receptor subfamily 1 group D member 1

1

11

High-throughput

0.489

High

885352

INHBE
Inhibin beta E chain

1

5

High-throughput

0.489

High

993902

PCDH1
Protocadherin-1

1

20

High-throughput

0.489

High

1048650

DSG2
Desmoglein-2

1

11

High-throughput

0.489

High

1119217

MBRL
Membralin

1

2

High-throughput

0.489

High

1120753

ACSM3
Acyl-coenzyme A synthetase ACSM3, mitochondrial

1

6

High-throughput

0.489

High

1137451

MCAF2
Activating transcription factor 7-interacting protein 2

1

1

High-throughput

0.489

High

1166663

LRIG3
Leucine-rich repeats and immunoglobulin-like domains protein 3

1

11

High-throughput

0.489

High

1294952

LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1

1

13

High-throughput

0.489

High

1305203

CNPY3
Protein canopy homolog 3

1

2

High-throughput

0.489

High

1305204

DDA1
DET1- and DDB1-associated protein 1

1

2

High-throughput

0.489

High

1305207

ANTR1
Anthrax toxin receptor 1

1

9

High-throughput

0.489

High

1305209

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

14

High-throughput

0.489

High

1305213

MAN1
Inner nuclear membrane protein Man1

1

10

High-throughput

0.489

High

1305215

SRPRB
Signal recognition particle receptor subunit beta

1

11

High-throughput

0.489

High

1305210

DDX4
Probable ATP-dependent RNA helicase DDX4

1

13

Small-scale

0.472

High

103833

G5E9A7
DM1 locus, WD repeat containing

1

17

High-throughput

0.470

High

231693

KIF1B
Kinesin-like protein KIF1B

1

20

High-throughput

0.470

High

557493

PECA1
Platelet endothelial cell adhesion molecule

1

16

High-throughput

0.470

High

1160561

Q6P9E2
RECK protein

1

1

High-throughput

0.470

High

328457

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

1

1

High-throughput

0.439

High

441559

MET
Hepatocyte growth factor receptor

1

20

Small-scale

0.437

High

92353

E9PB39
Rho guanine nucleotide exchange factor 10

1

16

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024