Protein: T22D3
TSC22 domain family protein 3 (DSIP-immunoreactive peptide) (Protein DIP) (hDIP) (Delta sleep-inducing peptide immunoreactor) (Glucocorticoid-induced leucine zipper protein) (GILZ) (TSC-22-like protein) (TSC-22-related protein) (TSC-22R)

Gene: T22D3, TSC22D3
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q99576

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0006970 - response to osmotic stress
GO:0070236 - negative regulation of activation-induced cell death of T cells

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1405420

T22D4
TSC22 domain family protein 4

4

10

High-throughput

0.892

High

1152461

T22D1
TSC22 domain family protein 1

3

10

High-throughput

0.861

High

273278

T22D2
TSC22 domain family protein 2

2

9

High-throughput

0.811

High

1405417

NRBP
Nuclear receptor-binding protein

5

15

Small-scale

0.659

High

1405410

T22D3
TSC22 domain family protein 3

1

9

Small-scale

0.647

High

1405421

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

3

0

High-throughput

0.646

High

401354

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

1

Small-scale

0.634

High

1048978

REL
Proto-oncogene c-Rel

2

5

High-throughput

0.606

High

64897

RCCD1
RCC1 domain-containing protein 1

2

0

High-throughput

0.602

High

1405413

IQCN
IQ domain-containing protein N

2

0

High-throughput

0.602

High

1322860

EID3
EP300-interacting inhibitor of differentiation 3

2

0

High-throughput

0.585

High

122973

SGK1
Serine/threonine-protein kinase Sgk1

2

3

Small-scale

0.584

High

1240807

F117B
Protein FAM117B

2

1

High-throughput

0.574

High

1405416

NRBP2
Nuclear receptor-binding protein 2

2

17

High-throughput

0.574

High

414478

P53
Cellular tumor antigen p53

1

1

Small-scale

0.561

High

626340

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

4

Small-scale

0.561

High

993722

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.561

High

1026764

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

4

Small-scale

0.561

High

537766

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.547

High

1244959

FIGL1
Fidgetin-like protein 1

1

1

High-throughput

0.536

High

1405412

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

3

High-throughput

0.536

High

320002

UFL1
E3 UFM1-protein ligase 1

1

0

Small-scale

0.526

High

316960

MTA2
Metastasis-associated protein MTA2

1

0

High-throughput

0.518

High

272738

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

0

High-throughput

0.513

High

1102069

PABP4
Polyadenylate-binding protein 4

1

0

High-throughput

0.513

High

1280103

UBE3D
E3 ubiquitin-protein ligase E3D

1

0

High-throughput

0.513

High

1323567

CMTR1
Cap-specific mRNA

1

0

High-throughput

0.513

High

1329829

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.513

High

1405411

DHRS6
Dehydrogenase/reductase SDR family member 6

1

0

High-throughput

0.513

High

1405418

FBX10
F-box only protein 10

1

0

High-throughput

0.513

High

370764

FOS
Protein c-Fos

1

1

Small-scale

0.501

High

51612

SPD2B
SH3 and PX domain-containing protein 2B

1

1

High-throughput

0.489

High

944418

SYJ2B
Synaptojanin-2-binding protein

1

2

High-throughput

0.489

High

1208325

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

1

High-throughput

0.489

High

1219102

C1QL3
Complement C1q-like protein 3

1

1

High-throughput

0.489

High

430269

JUN
Transcription factor Jun

1

0

Small-scale

0.480

High

991408

SUMO1
Small ubiquitin-related modifier 1

1

0

Small-scale

0.480

High

239610

MED14
Mediator of RNA polymerase II transcription subunit 14

1

1

Small-scale

0.479

High

404368

GCR
Glucocorticoid receptor

1

1

Small-scale

0.479

High

467797

MCR
Mineralocorticoid receptor

1

1

Small-scale

0.479

High

508495

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.479

High

581720

MYOD1
Myoblast determination protein 1

1

3

Small-scale

0.479

High

1110022

HDAC1
Histone deacetylase 1

1

1

Small-scale

0.479

High

1151286

MED1
Mediator of RNA polymerase II transcription subunit 1

1

1

Small-scale

0.479

High

1368079

HDAC2
Histone deacetylase 2

1

1

Small-scale

0.479

High

1399990

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

1

Small-scale

0.479

High

772412

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

Small-scale

0.458

High

848063

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

0

High-throughput

0.458

High

1028352

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

1132419

CASP8
Caspase-8

1

0

Small-scale

0.458

High

1277897

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1399417

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

1

0

High-throughput

0.458

High

231622

PRKY
Putative serine/threonine-protein kinase PRKY

1

4

High-throughput

0.445

High

902327

SCNNB
Epithelial sodium channel subunit beta

1

2

Small-scale

0.437

High

1198510

CEP55
Centrosomal protein of 55 kDa

2

0

High-throughput

0.328

High

1405415

C42S2
CDC42 small effector protein 2

2

0

High-throughput

0.328

High

1331298

ENDOV
Endonuclease V

2

0

High-throughput

0.318

High

1081594

BRME1
Break repair meiotic recombinase recruitment factor 1

1

0

High-throughput

0.299

High

1327404

DCLK2
Serine/threonine-protein kinase DCLK2

1

0

High-throughput

0.282

High

1405414

PKHF2
Pleckstrin homology domain-containing family F member 2

1

0

High-throughput

0.282

High

1405419

HPCL4
Hippocalcin-like protein 4

1

0

High-throughput

0.282

High

1363783

YLAT2
Y+L amino acid transporter 2

1

0

High-throughput

0.279

Low

1388937

ZHX1R
Zinc fingers and homeoboxes protein 1, isoform 2

1

0

High-throughput

0.279

Low

1402696

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025