HitPredict

Interactor 1: PD1L1 (Q9NZQ7)
Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (hPD-L1) (B7 homolog 1) (B7-H1) (CD antigen CD274)
Gene: CD274

Interactor 2: XPO7 (Q9UIA9)
Exportin-7 (Exp7) (Ran-binding protein 16)
Gene: XPO7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.50	0.633

Property	Details
Experiments	26186194, 28514442, 32941674, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 290 Hs			1 1087
+	Hs
		1249870 BTNL9_HUMAN (14-289): 1.16e-50: 176: 14.44		XPO7_HUMAN (1-1087): 0: 1234: 100.00
+	Hs
		1394325 VSIG2_HUMAN (3-270): 3.31e-40: 144: 15.11		XPO7_HUMAN (1-1087): 0: 1234: 100.00
+	Hs
		754121 CD80_HUMAN (28-259): 6.04e-30: 116: 21.07		XPO7_HUMAN (1-1087): 0: 1234: 100.00
+	Hs
		173480 PD1L1_HUMAN (1-290): 6.39e-63: 202: 100.00		XPO1_HUMAN (7-1074): 0: 815: 13.35
+	Hs
		172690 CXAR_HUMAN (3-281): 4.65e-40: 144: 16.67		XPO1_HUMAN (7-1074): 0: 815: 13.35
+	Hs
		173231 VSIG2_HUMAN (3-270): 3.31e-40: 144: 15.11		XPO1_HUMAN (7-1074): 0: 815: 13.35
+	Hs
		1421106 PD1L1_HUMAN (1-290): 6.39e-63: 202: 100.00		XPO4_HUMAN (4-1073): 0: 665: 17.43
+	Hs
		1249844 BTNL9_HUMAN (14-289): 1.16e-50: 176: 14.44		XPO4_HUMAN (4-1073): 0: 665: 17.43
+	Hs
		1394321 VSIG2_HUMAN (3-270): 3.31e-40: 144: 15.11		XPO4_HUMAN (4-1073): 0: 665: 17.43
+	Hs
		1401084 PD1L1_HUMAN (1-290): 6.39e-63: 202: 100.00		XPO6_HUMAN (1-1083): 1.5e-33: 142: 11.62
+	Hs
		1249834 BTNL9_HUMAN (14-289): 1.16e-50: 176: 14.44		XPO6_HUMAN (1-1083): 1.5e-33: 142: 11.62
+	Hs
		1394323 VSIG2_HUMAN (3-270): 3.31e-40: 144: 15.11		XPO5_HUMAN (6-239): 7.16e-43: 172: 15.14
+	Hs
		1394320 VSIG2_HUMAN (3-270): 3.31e-40: 144: 15.11		XPO6_HUMAN (1-1083): 1.5e-33: 142: 11.62
+	Hs
		221005 PD1L1_HUMAN (1-290): 6.39e-63: 202: 100.00		XPOT_HUMAN (12-229): 2.95e-11: 69.9: 13.84
+	Hs
		1453564 PD1L1_HUMAN (1-290): 6.39e-63: 202: 100.00		TNPO3_HUMAN (8-547): 6.8e-10: 65.6: 13.48
+	Hs
		754082 CD80_HUMAN (28-259): 6.04e-30: 116: 21.07		XPO6_HUMAN (1-1083): 1.5e-33: 142: 11.62
+	Hs
		1249881 BTNL9_HUMAN (14-289): 1.16e-50: 176: 14.44		TNPO3_HUMAN (8-547): 6.8e-10: 65.6: 13.48
+	Hs
		1394330 VSIG2_HUMAN (3-270): 3.31e-40: 144: 15.11		TNPO3_HUMAN (8-547): 6.8e-10: 65.6: 13.48
+	Hs
		754129 CD80_HUMAN (28-259): 6.04e-30: 116: 21.07		TNPO3_HUMAN (8-547): 6.8e-10: 65.6: 13.48
+	Hs
		845875 MUC18_HUMAN (20-245): 5.71e-12: 67.9: 17.17		TNPO3_HUMAN (8-547): 6.8e-10: 65.6: 13.48