HitPredict

Interactor 1: CD80 (P33681)
T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80)
Gene: CD80

Interactor 2: TNPO3 (Q9Y5L0)
Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR)
Gene: TNPO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 288 Hs			1 923
+	Hs
		1249881 BTNL9_HUMAN (29-286): 5.76e-52: 180: 16.05		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		1394330 VSIG2_HUMAN (6-287): 2.1e-42: 149: 15.54		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		172690 CXAR_HUMAN (18-283): 1.18e-42: 151: 17.83		XPO1_HUMAN (3-920): 6.79e-151: 475: 12.37
+	Hs
		173231 VSIG2_HUMAN (6-287): 2.1e-42: 149: 15.54		XPO1_HUMAN (3-920): 6.79e-151: 475: 12.37
+	Hs
		173480 PD1L1_HUMAN (19-275): 3.03e-40: 143: 20.15		XPO1_HUMAN (3-920): 6.79e-151: 475: 12.37
+	Hs
		334809 BTNL9_HUMAN (29-286): 5.76e-52: 180: 16.05		IPO7_HUMAN (13-813): 8.67e-101: 340: 11.63
+	Hs
		1249822 BTNL9_HUMAN (29-286): 5.76e-52: 180: 16.05		TNPO1_HUMAN (66-784): 4.01e-93: 316: 12.71
+	Hs
		164590 BTNL9_HUMAN (29-286): 5.76e-52: 180: 16.05		TNPO2_HUMAN (68-784): 3.35e-92: 313: 12.26
+	Hs
		334872 VSIG2_HUMAN (6-287): 2.1e-42: 149: 15.54		IPO7_HUMAN (13-813): 8.67e-101: 340: 11.63
+	Hs
		189196 BTNL9_HUMAN (29-286): 5.76e-52: 180: 16.05		IPO8_HUMAN (10-813): 5.23e-89: 307: 9.92
+	Hs
		164539 CD80_HUMAN (1-288): 1.16e-51: 172: 100.00		TNPO2_HUMAN (68-784): 3.35e-92: 313: 12.26
+	Hs
		1370988 VSIG2_HUMAN (6-287): 2.1e-42: 149: 15.54		TNPO1_HUMAN (66-784): 4.01e-93: 316: 12.71
+	Hs
		164626 VSIG2_HUMAN (6-287): 2.1e-42: 149: 15.54		TNPO2_HUMAN (68-784): 3.35e-92: 313: 12.26
+	Hs
		164655 PD1L1_HUMAN (19-275): 3.03e-40: 143: 20.15		TNPO2_HUMAN (68-784): 3.35e-92: 313: 12.26
+	Hs
		189291 PD1L1_HUMAN (19-275): 3.03e-40: 143: 20.15		IPO8_HUMAN (10-813): 5.23e-89: 307: 9.92
+	Hs
		134173 PD1L1_HUMAN (19-275): 3.03e-40: 143: 20.15		IPO5_HUMAN (68-703): 1.93e-86: 301: 13.24
+	Hs
		1394323 VSIG2_HUMAN (6-287): 2.1e-42: 149: 15.54		XPO5_HUMAN (9-614): 3.05e-22: 105: 14.21
+	Hs
		1134243 BTNL9_HUMAN (29-286): 5.76e-52: 180: 16.05		IMB1_HUMAN (38-691): 1.58e-09: 64.1: 9.56
+	Hs
		754024 CD80_HUMAN (1-288): 1.16e-51: 172: 100.00		IMB1_HUMAN (38-691): 1.58e-09: 64.1: 9.56
+	Hs
		1195637 VSIG2_HUMAN (6-287): 2.1e-42: 149: 15.54		Q4LE60_HUMAN (161-691): 3.1e-11: 69.5: 9.70