HitPredict

Interactor 1: RPB7 (O14459)
DNA-directed RNA polymerase II subunit rpb7 (RNA polymerase II subunit B7)
Gene: RPB7

Interactor 2: RPB4 (O74825)
DNA-directed RNA polymerase II subunit rpb4 (RNA polymerase II subunit B4)
Gene: RPB4

Species: Schizosaccharomyces pombe 972h-

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.881

Property	Details
Experiments	10523639, 15591044, 16204182, 15620689
Identification Methods	pull down, x-ray crystallography, affinity chromatography technology, biochemical, affinity technology
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	RNA_pol_Rpb4~S1, RNA_pol_Rpb4~SHS2_Rpb7-N
Common GO terms	GO:0005634 - nucleus GO:0005665 - RNA polymerase II, core complex GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0016591 - RNA polymerase II, holoenzyme GO:0031369 - translation initiation factor binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 172 Sp			1 135
+	Dm
		1364432 Q9VFB5_DROME (3-172): 8.45e-65: 197: 51.16		RPB4_DROME (2-134): 2.6e-47: 151: 38.81
+	Hs
		181407 RPB7_HUMAN (3-172): 7.42e-65: 197: 49.42		RPB4_HUMAN (6-134): 1.19e-45: 146: 40.77
+	Hs
		181486 RPC8_HUMAN (3-172): 2.89e-46: 152: 18.72		RPB4_HUMAN (6-134): 1.19e-45: 146: 40.77
+	Sc
		593053 RPB7_YEAST (3-172): 2.83e-65: 199: 52.94		RPB4_YEAST (55-133): 2.65e-21: 86.7: 47.50