HitPredict

Interactor 1: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, CH~EF-hand_7, CH~Spectrin, EF-hand_7~EF-hand_7, EF-hand_7~GAS2, EF-hand_7~Spectrin, Plectin~Plectin, SH3_10~Spectrin, SH3_10~Spectrin_3, Spectrin~Spectrin, Spectrin~Spectrin_3, Spectrin_2~Spectrin_2, Spectrin_2~Spectrin_3, Spectrin_3~Spectrin_3
Common GO terms GO:0003723 - RNA binding
GO:0003779 - actin binding
GO:0005198 - structural molecule activity
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
and 21 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 11Aug2025