HitPredict

Interactor 1: DYN3 (Q9UQ16)
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
Gene: DNM3

Interactor 2: SNX5 (Q9Y5X3)
Sorting nexin-5
Gene: SNX5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~PX
Common GO terms	GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 869 Hs			1 404
+	Hs
		1462313 DYN3_HUMAN (1-869): 0: 1080: 100.00		SNX6_HUMAN (10-404): 5.08e-109: 327: 64.81
+	Hs
		255502 DYN3_HUMAN (1-869): 0: 1080: 100.00		SNX2_HUMAN (19-403): 8.54e-91: 284: 24.15
+	Hs
		1111995 DYN3_HUMAN (1-869): 0: 1080: 100.00		SNX1_HUMAN (5-403): 5.9e-88: 277: 21.23
+	Hs
		1357703 DYN3_HUMAN (1-869): 0: 1080: 100.00		SNX33_HUMAN (1-403): 2.75e-75: 246: 13.48
+	Hs
		255399 DYN2_HUMAN (1-869): 0: 1041: 79.21		SNX2_HUMAN (19-403): 8.54e-91: 284: 24.15
+	Hs
		1462656 DYN3_HUMAN (1-869): 0: 1080: 100.00		SNX9_HUMAN (27-401): 1.34e-71: 237: 14.98
+	Hs
		896835 DYN2_HUMAN (1-869): 0: 1041: 79.21		SNX33_HUMAN (1-403): 2.75e-75: 246: 13.48
+	Hs
		1050702 DYN1_HUMAN (1-852): 0: 1035: 78.56		SNX33_HUMAN (1-403): 2.75e-75: 246: 13.48
+	Hs
		896948 DYN2_HUMAN (1-869): 0: 1041: 79.21		SNX9_HUMAN (27-401): 1.34e-71: 237: 14.98
+	Hs
		2961 A0A0D9SFE4_HUMAN (1-869): 0: 1037: 77.96		SNX9_HUMAN (27-401): 1.34e-71: 237: 14.98
+	Hs
		1050728 DYN1_HUMAN (1-852): 0: 1035: 78.56		SNX9_HUMAN (27-401): 1.34e-71: 237: 14.98
+	Hs
		896862 DYN2_HUMAN (1-869): 0: 1041: 79.21		SNX18_HUMAN (18-362): 5.87e-67: 225: 13.64
+	Ce
		810578 DYN1_CAEEL (3-815): 0: 946: 62.09		LST4_CAEEL (30-402): 6.22e-63: 213: 13.81