HitPredict

Interactor 1: SNX2 (O60749)
Sorting nexin-2 (Transformation-related gene 9 protein) (TRG-9)
Gene: SNX2

Interactor 2: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PX
Common GO terms	GO:0005737 - cytoplasm GO:0005768 - endosome GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 519 Hs			1 870
+	Hs
		255502 SNX2_HUMAN (1-519): 5.72e-150: 440: 100.00		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		1111995 SNX1_HUMAN (2-519): 1.55e-123: 373: 59.32		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		896948 SNX9_HUMAN (3-515): 6.17e-93: 296: 16.64		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		896862 SNX18_HUMAN (4-474): 2.53e-78: 259: 15.31		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		896835 SNX33_HUMAN (47-518): 7.25e-78: 256: 14.52		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		1050728 SNX9_HUMAN (3-515): 6.17e-93: 296: 16.64		DYN1_HUMAN (1-846): 0: 1002: 79.04
+	Hs
		1462656 SNX9_HUMAN (3-515): 6.17e-93: 296: 16.64		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		2961 SNX9_HUMAN (3-515): 6.17e-93: 296: 16.64		A0A0D9SFE4_HUMAN (1-851): 0: 994: 78.11
+	Hs
		1050702 SNX33_HUMAN (47-518): 7.25e-78: 256: 14.52		DYN1_HUMAN (1-846): 0: 1002: 79.04
+	Hs
		1357703 SNX33_HUMAN (47-518): 7.25e-78: 256: 14.52		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		1462657 SNX5_HUMAN (123-517): 2.29e-68: 227: 22.89		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		1462313 SNX6_HUMAN (113-517): 4.07e-68: 226: 19.06		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Ce
		810578 LST4_CAEEL (2-516): 6.86e-68: 230: 15.27		DYN1_CAEEL (3-823): 0: 899: 61.86