HitPredict

Interactor 1: KMT2B (O08550)
Histone-lysine N-methyltransferase 2B (Lysine N-methyltransferase 2B) (EC 2.1.1.364) (Myeloid/lymphoid or mixed-lineage leukemia protein 4 homolog) (Trithorax homolog 2) (WW domain-binding protein 7) (WBP-7)
Gene: KMT2B

Interactor 2: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23892456
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2713 Mm			1 305
+	Mm
		1283119 NSD2_MOUSE (2531-2712): 3.7e-55: 215: 28.65		NANOG_MOUSE (1-305): 1.88e-60: 196: 100.00
+	Mm
		866403 KMT2A_MOUSE (1789-2713): 2.16e-62: 241: 32.00		PAX7_MOUSE (80-304): 7.09e-33: 128: 14.64
+	Mm
		840137 NSD2_MOUSE (2531-2712): 3.7e-55: 215: 28.65		NKX25_MOUSE (23-199): 8.33e-44: 153: 25.76
+	Dm
		1268939 TRR_DROME (1580-1817): 2.12e-60: 233: 28.24		Q7KS72_DROME (35-207): 1.63e-27: 111: 24.31
+	Mm
		1222435 EZH2_MOUSE (2567-2695): 1.15e-16: 89: 39.54		NANOG_MOUSE (1-305): 1.88e-60: 196: 100.00
+	Mm
		107471 F8WI37_MOUSE (273-980): 4.93e-12: 74.7: 13.21		NANOG_MOUSE (1-305): 1.88e-60: 196: 100.00
+	Mm
		1283117 KMT2C_MOUSE (273-980): 4.89e-12: 74.7: 13.21		NANOG_MOUSE (1-305): 1.88e-60: 196: 100.00
+	Hs
		161408 KMT2D_HUMAN (1601-1700): 6.46e-10: 67.7: 29.70		PAX7_HUMAN (80-304): 1.42e-34: 133: 15.06
+	Dm
		1465720 Q9W1H0_DROME (1577-1701): 5.02e-11: 71.1: 21.26		Q9V490_DROME (61-297): 3.93e-33: 129: 14.05
+	Hs
		662249 KMT2C_HUMAN (1816-2372): 4.41e-09: 64.7: 15.83		PAX7_HUMAN (80-304): 1.42e-34: 133: 15.06
+	Hs
		161417 KMT2D_HUMAN (1601-1700): 6.46e-10: 67.7: 29.70		TLX1_HUMAN (29-215): 7.18e-34: 128: 22.80
+	Hs
		725285 KMT2C_HUMAN (1816-2372): 4.41e-09: 64.7: 15.83		TLX1_HUMAN (29-215): 7.18e-34: 128: 22.80
+	Hs
		161412 KMT2D_HUMAN (1601-1700): 6.46e-10: 67.7: 29.70		PAX6_HUMAN (46-285): 2.02e-31: 123: 14.82
+	Hs
		161402 KMT2D_HUMAN (1601-1700): 6.46e-10: 67.7: 29.70		HXB2_HUMAN (4-305): 1.46e-31: 122: 17.88
+	Hs
		685267 KMT2C_HUMAN (1816-2372): 4.41e-09: 64.7: 15.83		PAX6_HUMAN (46-285): 2.02e-31: 123: 14.82
+	Hs
		161379 KMT2D_HUMAN (1601-1700): 6.46e-10: 67.7: 29.70		TLX2_HUMAN (60-158): 7.64e-27: 108: 30.39
+	Hs
		226574 KMT2C_HUMAN (1816-2372): 4.41e-09: 64.7: 15.83		TLX2_HUMAN (60-158): 7.64e-27: 108: 30.39
+	Hs
		161378 KMT2D_HUMAN (1601-1700): 6.46e-10: 67.7: 29.70		TLX3_HUMAN (89-153): 9.36e-09: 57.4: 43.08
+	Hs
		225064 KMT2C_HUMAN (1816-2372): 4.41e-09: 64.7: 15.83		TLX3_HUMAN (89-153): 9.36e-09: 57.4: 43.08