HitPredict

Interactor 1: Q9VJI7 (Q9VJI7)
U6 snRNA-associated Sm-like protein LSm7
Gene: LSm7

Interactor 2: Q9VRT7 (Q9VRT7)
U6 snRNA-associated Sm-like protein LSm5
Gene: BcDNA:RE60135

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.835

Property	Details
Experiments	14605208, 20353594, 38944040
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005688 - U6 snRNP GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 110 Dm			1 91
+	Hs
		1460920 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		LSM5_HUMAN (3-91): 1.64e-33: 112: 79.78
+	Mm
		974896 LSM7_MOUSE (13-110): 1.55e-33: 113: 75.51		LSM5_MOUSE (3-91): 1.64e-33: 112: 79.78
+	Ce
		198255 Q23543_CAEEL (10-110): 8.94e-32: 109: 56.44		O18694_CAEEL (3-91): 3.87e-34: 114: 71.91
+	Dm
		1303480 Q9VJI7_DROME (1-110): 6.02e-39: 127: 100.00		Q8IMX8_DROME (6-88): 5.69e-26: 93.8: 20.43
+	Dm
		1478476 Q9VJI7_DROME (1-110): 6.02e-39: 127: 100.00		RUXE_DROME (5-91): 6.08e-26: 93.4: 24.18
+	Hs
		973844 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		RUXE_HUMAN (7-85): 3.37e-27: 96.5: 25.30
+	Sp
		207092 LSM7_SCHPO (6-109): 2.38e-34: 116: 50.96		LSM5_SCHPO (12-90): 4.7e-26: 93.4: 51.90
+	At
		1319289 LSM7_ARATH (17-109): 1.31e-32: 111: 61.29		Q8LAK5_ARATH (4-88): 9.65e-28: 97.7: 25.84
+	At
		1456573 LSM7_ARATH (17-109): 1.31e-32: 111: 61.29		Q9ZV45_ARATH (4-88): 4.94e-27: 96.1: 25.84
+	Hs
		974292 LSM7_HUMAN (13-110): 5.98e-34: 114: 76.53		LSM3_HUMAN (7-86): 4.4e-23: 86.5: 24.44
+	Sc
		818474 LSM7_YEAST (2-101): 2.51e-29: 103: 43.14		LSM5_YEAST (9-88): 1.55e-23: 87.3: 38.82
+	Hs
		973680 LSM3_HUMAN (1-96): 2.87e-25: 92.7: 27.72		RUXE_HUMAN (7-85): 3.37e-27: 96.5: 25.30
+	Sc
		924553 LSM7_YEAST (2-101): 2.51e-29: 103: 43.14		LSM3_YEAST (12-91): 1.94e-22: 84.6: 21.43
+	Dm
		1052578 RSMB_DROME (24-95): 1.98e-24: 93.4: 26.03		RUXE_DROME (5-91): 6.08e-26: 93.4: 24.18
+	Sc
		818463 LSM1_YEAST (3-102): 5.6e-27: 99.2: 25.23		LSM5_YEAST (9-88): 1.55e-23: 87.3: 38.82
+	Sc
		864124 LSM1_YEAST (3-102): 5.6e-27: 99.2: 25.23		LSM3_YEAST (12-91): 1.94e-22: 84.6: 21.43
+	Sp
		267772 LSM7_SCHPO (6-109): 2.38e-34: 116: 50.96		LSM7_SCHPO (4-85): 6.12e-15: 66.1: 23.26
+	At
		1320158 LSM1B_ARATH (23-106): 4.9e-26: 95.4: 28.57		LSM7_ARATH (21-91): 3.44e-16: 68.8: 21.05
+	Sc
		864121 LSM1_YEAST (3-102): 5.6e-27: 99.2: 25.23		LSM7_YEAST (21-86): 4.98e-11: 56.1: 28.38
+	Dm
		1052597 RSMB_DROME (24-95): 1.98e-24: 93.4: 26.03		RUXG_DROME (19-84): 1.54e-13: 61.5: 27.27