HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: CUX1 (P39880)
Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (CDP/Cux p200) (Homeobox protein cux-1) [Cleaved into: CDP/Cux p110]
Gene: CUX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 1505
+	Hs
		148460 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH9_HUMAN (384-1281): 7.42e-17: 89.4: 7.20
+	Hs
		148466 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH11_HUMAN (1-422): 6.6e-15: 82.8: 11.92
+	Hs
		148461 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH10_HUMAN (1-336): 1.78e-11: 71.7: 12.87
+	Hs
		148801 CTRO_HUMAN (1-2027): 0: 1212: 100.00		DCTN1_HUMAN (99-440): 7.32e-11: 69.3: 15.90
+	Rn
		92843 CTRO_RAT (1-2027): 0: 1136: 93.58		ROCK2_RAT (8-434): 4.25e-17: 90.1: 18.09
+	Hs
		116964 SGK1_HUMAN (59-407): 8.42e-121: 390: 31.37		MYH1_HUMAN (100-1048): 3.46e-31: 136: 7.56
+	Hs
		725079 ST38L_HUMAN (74-430): 6.61e-69: 242: 35.79		MYH9_HUMAN (384-1281): 7.42e-17: 89.4: 7.20
+	Bt
		1100183 ROCK2_BOVIN (849-1552): 9.07e-35: 148: 8.35		ROCK2_BOVIN (8-434): 5.4e-18: 92.7: 18.92
+	Rn
		222472 MRCKA_RAT (536-1070): 1.62e-33: 144: 11.97		MRCKA_RAT (147-636): 3.85e-18: 93.2: 13.07
+	Rn
		222476 MRCKA_RAT (536-1070): 1.62e-33: 144: 11.97		MRCKB_RAT (63-422): 5.43e-18: 92.7: 15.37
+	Hs
		1137917 MRCKB_HUMAN (569-1070): 4.13e-33: 143: 12.04		MRCKA_HUMAN (147-416): 5.82e-18: 92.9: 14.48
+	Rn
		1186812 MRCKB_RAT (566-1070): 2.51e-33: 143: 12.74		MRCKB_RAT (63-422): 5.43e-18: 92.7: 15.37
+	Hs
		1137871 MRCKA_HUMAN (536-1061): 4.38e-32: 139: 11.82		MRCKA_HUMAN (147-416): 5.82e-18: 92.9: 14.48
+	Hs
		724810 ROCK1_HUMAN (1051-1566): 8.4e-21: 102: 10.08		MYH9_HUMAN (384-1281): 7.42e-17: 89.4: 7.20
+	Hs
		254476 ROCK1_HUMAN (1051-1566): 8.4e-21: 102: 10.08		ROCK2_HUMAN (8-434): 1.11e-16: 88.5: 18.71