HitPredict

Interactor 1: DMXL1 (Q9Y485)
DmX-like protein 1 (X-like 1 protein)
Gene: DMXL1

Interactor 2: WDR7 (Q9Y4E6)
WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG)
Gene: WDR7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 3027 Hs			1 1490
+	Hs
		1351323 DMXL2_HUMAN (1-3019): 0: 3752: 54.84		WDR7_HUMAN (1-1490): 0: 1524: 98.26
+	Mm
		1297215 DMXL2_MOUSE (1-3019): 0: 3748: 54.73		WDR7_MOUSE (1-1490): 0: 1492: 93.31
+	Mm
		72853 B0V2P5_MOUSE (1-3019): 0: 3728: 54.32		WDR7_MOUSE (1-1490): 0: 1492: 93.31
+	Hs
		845250 LIS1_HUMAN (2720-3025): 3.16e-78: 268: 13.76		LIS1_HUMAN (206-548): 1.56e-38: 151: 10.06
+	Mm
		988931 LIS1_MOUSE (2720-3025): 3.07e-78: 268: 13.76		LIS1_MOUSE (206-548): 1.41e-38: 151: 10.06
+	Hs
		845264 LIS1_HUMAN (2720-3025): 3.16e-78: 268: 13.76		WDR5_HUMAN (669-902): 4.4e-30: 124: 9.83
+	Hs
		965071 WDR5_HUMAN (2564-2913): 6.1e-65: 227: 11.24		WDR5B_HUMAN (16-237): 2.3e-31: 128: 13.00
+	Dm
		1463899 WDS_DROME (2608-2917): 9.54e-66: 230: 12.03		WDS_DROME (669-902): 2.68e-29: 123: 10.26
+	Hs
		964797 WDR5_HUMAN (2564-2913): 6.1e-65: 227: 11.24		WDR5_HUMAN (669-902): 4.4e-30: 124: 9.83
+	Hs
		965276 WDR5_HUMAN (2564-2913): 6.1e-65: 227: 11.24		NLE1_HUMAN (666-860): 1.18e-23: 108: 7.46
+	Hs
		222461 WDR5_HUMAN (2564-2913): 6.1e-65: 227: 11.24		PLRG1_HUMAN (635-935): 5.66e-23: 106: 7.69
+	Hs
		845346 LIS1_HUMAN (2720-3025): 3.16e-78: 268: 13.76		KTNB1_HUMAN (19-211): 7.11e-09: 62.6: 14.87
+	Hs
		965141 WDR5_HUMAN (2564-2913): 6.1e-65: 227: 11.24		FBXW7_HUMAN (666-882): 2.96e-21: 102: 11.52
+	Hs
		964894 WDR5_HUMAN (2564-2913): 6.1e-65: 227: 11.24		TBL3_HUMAN (569-810): 6.85e-19: 95.3: 8.73
+	Dm
		1463921 WDS_DROME (2608-2917): 9.54e-66: 230: 12.03		Q9VYQ9_DROME (95-434): 3.19e-17: 88.7: 8.50
+	Hs
		1334151 POC1B_HUMAN (2567-2901): 6.32e-53: 196: 11.33		POC1A_HUMAN (412-663): 1.26e-25: 113: 16.22
+	Hs
		597351 GBB1_HUMAN (2610-2956): 9.84e-56: 200: 14.86		GBB3_HUMAN (458-718): 4.45e-20: 95.3: 15.09
+	Hs
		163628 GBB1_HUMAN (2610-2956): 9.84e-56: 200: 14.86		GNB5_HUMAN (455-635): 6.88e-19: 93: 16.00