Interactor 1: ANM5 (O14744)
Protein arginine N-methyltransferase 5 (PRMT5) (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed]
Gene: PRMT5

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 25713080, 18404153, 29227283, 35046516, 14559996, 15670829, 15485929, 23071334, 20951943
Identification Methods unspecified method, enzymatic study, affinity chromatography technology, methyltransferase assay
Interaction Type direct interaction, physical association, methylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0046982 - protein heterodimerization activity
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 637
Hs

1 103
+ At
+ Dm
+ Hs
+ Hs
+ Dm
+ At
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024