HitPredict

Interactor 1: GNB5 (O14775)
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)
Gene: GNB5

Interactor 2: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26186194
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 395 Hs			1 556
+	Hs
		154662 GNB5_HUMAN (1-395): 3.65e-115: 342: 100.00		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		154696 GNB5_HUMAN (1-395): 3.65e-115: 342: 100.00		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		154661 GNB5_HUMAN (1-395): 3.65e-115: 342: 100.00		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Sc
		519891 GBB_YEAST (30-395): 7.35e-99: 302: 34.15		TCPA_YEAST (4-542): 0: 558: 62.57
+	Sc
		579422 GBB_YEAST (30-395): 7.35e-99: 302: 34.15		TCPG_YEAST (1-538): 0: 552: 29.20
+	Hs
		573346 WDR5B_HUMAN (10-266): 2.12e-67: 218: 16.73		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		573204 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		826748 WDR5B_HUMAN (10-266): 2.12e-67: 218: 16.73		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		826604 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		1202777 WDR5B_HUMAN (10-266): 2.12e-67: 218: 16.73		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		921038 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		1306704 NLE1_HUMAN (9-266): 1.37e-56: 194: 14.71		TCPH_HUMAN (1-545): 0: 566: 34.84
+	Hs
		573384 POC1B_HUMAN (277-395): 1.41e-31: 126: 26.89		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		573371 POC1A_HUMAN (269-395): 1.52e-28: 117: 24.41		TCPA_HUMAN (1-556): 0: 630: 100.00
+	Hs
		821156 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Hs
		821437 NLE1_HUMAN (9-266): 1.37e-56: 194: 14.71		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Hs
		826784 POC1B_HUMAN (277-395): 1.41e-31: 126: 26.89		TCPG_HUMAN (5-550): 0: 593: 33.03
+	Hs
		821326 POC1B_HUMAN (277-395): 1.41e-31: 126: 26.89		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Hs
		821316 POC1A_HUMAN (269-395): 1.52e-28: 117: 24.41		TCPE_HUMAN (4-530): 0: 550: 31.96
+	Sc
		579432 GBB_YEAST (30-395): 7.35e-99: 302: 34.15		TCPH_YEAST (10-531): 1.74e-87: 282: 35.10