Interactor 1: GNB5 (O14775)
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)
Gene: GNB5

Interactor 2: RGS6 (P49758)
Regulator of G-protein signaling 6 (RGS6) (S914)
Gene: RGS6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.899

The method score is based on:

Property Details
Experiments 33961781, 28514442, 10521509, 10339615
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEP~WD40, G-gamma~WD40, RGS~WD40, RGS_DHEX~WD40
Common GO terms GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 395
Hs

1 472
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Bt
+ Ce
+ Ce
+ Ce
+ Ce

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Last updated: 15 Jul 2024