HitPredict

Interactor 1: TCRG1 (O14776)
Transcription elongation regulator 1 (TATA box-binding protein-associated factor 2S) (Transcription factor CA150)
Gene: TCERG1

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	32707033, 36244648
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1098 Hs			1 648
+	Hs
		263469 PR40A_HUMAN (342-1079): 1.36e-67: 247: 18.03		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374148 RHG05_HUMAN (678-1075): 1.41e-54: 210: 15.37		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		375013 CHD7_HUMAN (126-1052): 3.65e-12: 73.4: 9.23		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Dm
		507730 Q8MLP1_DROME (111-1068): 2.26e-42: 171: 10.65		KRAF1_DROME (45-647): 6.35e-165: 491: 44.98
+	Dm
		507767 Q9W179_DROME (111-1068): 1.28e-41: 169: 10.65		KRAF1_DROME (45-647): 6.35e-165: 491: 44.98
+	Hs
		542878 MDC1_HUMAN (24-892): 5.83e-33: 141: 9.38		BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88
+	Hs
		542914 WWP1_HUMAN (269-580): 3.25e-26: 118: 14.99		BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88
+	Hs
		522749 MUC1_HUMAN (13-554): 3.83e-23: 108: 11.50		SRC_HUMAN (331-607): 3.01e-106: 333: 33.45