Interactor 1: PTPRT (O14522)
Receptor-type tyrosine-protein phosphatase T (R-PTP-T) (EC 3.1.3.48) (Receptor-type tyrosine-protein phosphatase rho) (RPTP-rho)
Gene: PTPRT
Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21725282 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH2~fn3, SH2~Y_phosphatase |
| Common GO terms | GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0019903 - protein phosphatase binding |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Last updated: 11Aug2025