HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: LUZP1 (Q86V48)
Leucine zipper protein 1 (Filamin mechanobinding actin cross-linking protein) (Fimbacin)
Gene: LUZP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2027 Hs			1 1076
+	Hs
		157688 CTRO_HUMAN (1-2027): 0: 1239: 100.00		MY18A_HUMAN (72-652): 1.93e-31: 136: 12.91
+	Hs
		157021 CTRO_HUMAN (1-2027): 0: 1239: 100.00		MYH10_HUMAN (1-608): 3.08e-28: 125: 11.11
+	Hs
		156684 CTRO_HUMAN (1-2027): 0: 1239: 100.00		CTRO_HUMAN (27-558): 1.53e-24: 113: 12.04
+	Hs
		157026 CTRO_HUMAN (1-2027): 0: 1239: 100.00		MYH11_HUMAN (3-537): 2.17e-23: 109: 13.19
+	Hs
		156919 CTRO_HUMAN (1-2027): 0: 1239: 100.00		DESP_HUMAN (44-616): 3.94e-15: 82.9: 10.48
+	Hs
		157020 CTRO_HUMAN (1-2027): 0: 1239: 100.00		MYH9_HUMAN (1-353): 3.2e-12: 73.3: 13.65
+	Hs
		157401 CTRO_HUMAN (1-2027): 0: 1239: 100.00		PLEC_HUMAN (35-503): 1.33e-11: 71.4: 16.50
+	Rn
		97302 CTRO_RAT (1-2027): 0: 1164: 93.58		ROCK2_RAT (1-464): 1.88e-24: 113: 12.88
+	Hs
		1217526 MRCKA_HUMAN (26-941): 1.68e-134: 466: 25.40		MRCKA_HUMAN (226-673): 1.22e-21: 104: 10.11
+	Hs
		1217577 MRCKA_HUMAN (26-941): 1.68e-134: 466: 25.40		MRCKB_HUMAN (255-633): 9e-21: 101: 11.11
+	Rn
		930649 AAPK1_RAT (73-602): 1.48e-116: 383: 18.22		MYH10_RAT (103-948): 5.65e-31: 134: 9.67
+	Hs
		122910 SGK1_HUMAN (59-407): 1.34e-121: 393: 31.37		MYH1_HUMAN (2-264): 3.68e-09: 63.2: 13.60
+	Rn
		930605 AAPK1_RAT (73-602): 1.48e-116: 383: 18.22		MYH9_RAT (399-768): 2.3e-09: 64: 7.28
+	Hs
		157903 LATS2_HUMAN (103-400): 4.89e-58: 222: 39.26		CTRO_HUMAN (27-558): 1.53e-24: 113: 12.04
+	Hs
		563078 MYH8_HUMAN (647-1594): 4.71e-54: 212: 12.02		MYH13_HUMAN (168-817): 6.99e-24: 111: 10.46
+	Hs
		563056 MYH8_HUMAN (647-1594): 4.71e-54: 212: 12.02		EEA1_HUMAN (1-532): 6.87e-22: 104: 10.40
+	Hs
		773091 ST38L_HUMAN (74-430): 6.63e-69: 242: 35.79		MYH9_HUMAN (1-353): 3.2e-12: 73.3: 13.65
+	Mm
		563088 MYH8_MOUSE (399-1296): 3.56e-54: 212: 13.42		MYH6_MOUSE (3-524): 7.14e-21: 101: 9.59
+	Hs
		563081 MYH8_HUMAN (647-1594): 4.71e-54: 212: 12.02		MYH4_HUMAN (3-525): 2.84e-20: 99.8: 10.11
+	Hs
		556892 MYH7_HUMAN (641-1590): 1.4e-45: 184: 10.50		MYH7_HUMAN (5-340): 3.18e-10: 66.7: 13.49