Interactor 1: IKKB (O14920)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK-2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: IKBKB

Interactor 2: TPX2 (Q9ULW0)
Targeting protein for Xklp2 (Differentially expressed in cancerous and non-cancerous lung cells 2) (DIL-2) (Hepatocellular carcinoma-associated antigen 519) (Hepatocellular carcinoma-associated antigen 90) (Protein fls353) (Restricted expression proliferation-associated protein 100) (p100)
Gene: TPX2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 17939994
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Aurora-A_bind~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 756
Hs

1 747
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024