HitPredict

Interactor 1: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Interactor 2: DUS10 (Q9Y6W6)
Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5)
Gene: DUSP10

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	27880917, 28675297
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DSPc~Pkinase, Pkinase~Rhodanese
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 926 Hs			1 482
+	Hs
		159176 CSKP_HUMAN (1-926): 0: 973: 100.00		DUS3_HUMAN (288-470): 2.15e-53: 179: 29.32
+	Hs
		1021597 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		DUS10_HUMAN (1-482): 0: 632: 100.00
+	Hs
		942407 DLG4_HUMAN (402-922): 1.14e-145: 451: 22.56		DUS10_HUMAN (1-482): 0: 632: 100.00
+	Mm
		1143521 DLG4_MOUSE (402-922): 5.68e-145: 449: 22.37		DUS10_MOUSE (1-482): 0: 632: 96.48
+	Hs
		1132904 MPP7_HUMAN (354-926): 1.78e-145: 445: 30.81		DUS10_HUMAN (1-482): 0: 632: 100.00
+	Hs
		1039127 KCC2D_HUMAN (8-312): 3.56e-88: 291: 47.71		SSH3_HUMAN (291-479): 2.41e-59: 208: 26.98