Interactor 1: DVL1 (O14640)
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)
Gene: DVL1
Interactor 2: FZD7 (O75084)
Frizzled-7 (Fz-7) (hFz7) (FzE3)
Gene: FZD7
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26126266 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DEP~Frizzled |
| Common GO terms | GO:0005109 - frizzled binding GO:0006355 - regulation of DNA-templated transcription GO:0035567 - non-canonical Wnt signaling pathway GO:0060070 - canonical Wnt signaling pathway GO:0060071 - Wnt signaling pathway, planar cell polarity pathway |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025