Protein: FZD2
Frizzled-2 (Fz-2) (hFz2) (FzE2)

Gene: FZD2
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q14332

Gene Ontology (top 5):
GO:0003149 - membranous septum morphogenesis
GO:0003150 - muscular septum morphogenesis
GO:0003151 - outflow tract morphogenesis
GO:0004930 - G protein-coupled receptor activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

942152

WNT3A
Protein Wnt-3a

2

20

Small-scale

0.768

High

270455

FZD7
Frizzled-7

1

12

High-throughput

0.691

High

1125842

EREP1
Endosomal transmembrane epsin interactor 1

3

1

High-throughput

0.667

High

1125851

S39A4
Zinc transporter ZIP4

3

5

High-throughput

0.650

High

1125858

LYPD6
Ly6/PLAUR domain-containing protein 6

3

0

High-throughput

0.638

High

540453

LAMP1
Lysosome-associated membrane glycoprotein 1

2

1

High-throughput

0.628

High

1125856

TM11B
Transmembrane protease serine 11B

2

3

High-throughput

0.628

High

1125859

AGRG5
Adhesion G-protein coupled receptor G5

2

6

High-throughput

0.628

High

1125871

GPR21
Probable G-protein coupled receptor 21

2

3

High-throughput

0.628

High

833462

WNT5A
Protein Wnt-5a

1

20

Small-scale

0.618

High

1125845

ZACN
Ligand-gated cation channel ZACN

2

6

High-throughput

0.611

High

1125868

5HT3C
5-hydroxytryptamine receptor 3C

2

4

High-throughput

0.611

High

1125879

GPR52
G-protein coupled receptor 52

2

3

High-throughput

0.611

High

845509

PI2R
Prostacyclin receptor

2

0

High-throughput

0.602

High

1125876

NRN1
Neuritin

2

0

High-throughput

0.602

High

1005538

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

2

5

High-throughput

0.558

High

1125860

SYNE4
Nesprin-4

2

2

High-throughput

0.558

High

132593

UPK1A
Uroplakin-1a

1

9

High-throughput

0.536

High

248469

O10H2
Olfactory receptor 10H2

1

4

High-throughput

0.536

High

338688

VNN2
Pantetheine hydrolase VNN2

1

3

High-throughput

0.536

High

349419

TSN15
Tetraspanin-15

1

4

High-throughput

0.536

High

476499

STS
Steryl-sulfatase

1

1

High-throughput

0.536

High

688663

NKG2C
NKG2-C type II integral membrane protein

1

4

High-throughput

0.536

High

771770

SCN4A
Sodium channel protein type 4 subunit alpha

1

4

High-throughput

0.536

High

868294

P2RY1
P2Y purinoceptor 1

1

1

High-throughput

0.536

High

1032581

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

4

High-throughput

0.536

High

1125846

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

1

High-throughput

0.536

High

1125847

S39AC
Zinc transporter ZIP12

1

5

High-throughput

0.536

High

1125853

LRC55
Leucine-rich repeat-containing protein 55

1

1

High-throughput

0.536

High

1125857

TMPSC
Transmembrane protease serine 12

1

3

High-throughput

0.536

High

1125864

SIDT2
SID1 transmembrane family member 2

1

1

High-throughput

0.536

High

1125865

OR1M1
Olfactory receptor 1M1

1

5

High-throughput

0.536

High

1125873

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.536

High

1125874

RXFP1
Relaxin receptor 1

1

1

High-throughput

0.536

High

1125878

CLC2D
C-type lectin domain family 2 member D

1

4

High-throughput

0.536

High

1008033

KCJ10
ATP-sensitive inward rectifier potassium channel 10

1

0

High-throughput

0.513

High

1125855

TMC4
Voltage-gated chloride channel TMC4

1

0

High-throughput

0.513

High

1125863

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

0

High-throughput

0.513

High

1125866

LHPL5
LHFPL tetraspan subfamily member 5 protein

1

0

High-throughput

0.513

High

1125875

KCMB3
Calcium-activated potassium channel subunit beta-3

1

0

High-throughput

0.513

High

317064

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

1

High-throughput

0.489

High

907238

ARSL
Arylsulfatase L

1

1

High-throughput

0.489

High

1085318

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

4

High-throughput

0.489

High

1125843

CL12B
C-type lectin domain family 12 member B

1

4

High-throughput

0.489

High

1125850

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

6

High-throughput

0.489

High

1125867

SG1C1
Secretoglobin family 1C member 1

1

2

High-throughput

0.489

High

1125870

TM169
Transmembrane protein 169

1

3

High-throughput

0.489

High

1006063

DLG4
Disks large homolog 4

1

13

Small-scale

0.481

High

363285

EGFR
Epidermal growth factor receptor

1

5

High-throughput

0.479

High

410840

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

5

High-throughput

0.479

High

774354

BASI
Basigin

1

4

High-throughput

0.479

High

1101725

PTK7
Inactive tyrosine-protein kinase 7

1

6

High-throughput

0.479

High

827778

STAT3
Signal transducer and activator of transcription 3

1

0

Small-scale

0.458

High

669321

ACKR3
Atypical chemokine receptor 3

1

3

High-throughput

0.445

High

868053

OR1D4
Olfactory receptor 1D4

1

5

High-throughput

0.445

High

886052

CXCR3
C-X-C chemokine receptor type 3

1

2

High-throughput

0.445

High

1125869

S47A1
Multidrug and toxin extrusion protein 1

1

2

High-throughput

0.445

High

1125877

S52A3
Solute carrier family 52, riboflavin transporter, member 3

1

1

High-throughput

0.445

High

1125861

SVOP
Synaptic vesicle 2-related protein

1

3

High-throughput

0.407

High

1125848

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.328

High

1125844

CO032
Uncharacterized protein C15orf32

1

0

High-throughput

0.279

Low

1125849

KCP3
Keratinocyte-associated protein 3

1

0

High-throughput

0.279

Low

1125852

TM107
Transmembrane protein 107

1

0

High-throughput

0.279

Low

1125854

SMIM5
Small integral membrane protein 5

1

0

High-throughput

0.279

Low

1125862

VMA12
Vacuolar ATPase assembly protein VMA12

1

0

High-throughput

0.279

Low

1125872

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025