HitPredict

Interactor 1: ML12B (O14950)
Myosin regulatory light chain 12B (MLC-2A) (MLC-2) (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) (SHUJUN-1)
Gene: MYL12B

Interactor 2: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	26209609
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 172 Hs			1 372
+	Hs
		580628 ML12A_HUMAN (15-172): 2.3e-65: 199: 99.37		CDK9_HUMAN (1-372): 2.88e-147: 422: 100.00
+	Hs
		159545 ML12B_HUMAN (1-172): 1.42e-67: 204: 100.00		CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76
+	At
		1106294 CDPK3_ARATH (103-172): 4.65e-14: 70.6: 22.86		MPK4_ARATH (7-362): 1.97e-137: 397: 29.41
+	At
		1106402 CDPKU_ARATH (87-172): 5.02e-13: 67.6: 29.07		MPK4_ARATH (7-362): 1.97e-137: 397: 29.41
+	At
		1106366 CML11_ARATH (102-171): 1.59e-12: 64: 22.86		MPK4_ARATH (7-362): 1.97e-137: 397: 29.41
+	At
		483191 CALM3_ARATH (32-93): 2.72e-12: 62.8: 33.33		MPK4_ARATH (7-362): 1.97e-137: 397: 29.41
+	At
		1106160 CDPK3_ARATH (103-172): 4.65e-14: 70.6: 22.86		MPK3_ARATH (8-353): 3.04e-133: 387: 28.82
+	At
		483079 CALM4_ARATH (98-171): 7.33e-17: 74.9: 24.32		MPK1_ARATH (3-368): 1.74e-131: 382: 31.42
+	At
		1106059 CDPK3_ARATH (103-172): 4.65e-14: 70.6: 22.86		MPK2_ARATH (3-363): 6.43e-132: 384: 31.03
+	At
		1106416 CDPK3_ARATH (103-172): 4.65e-14: 70.6: 22.86		MPK5_ARATH (7-362): 3.2e-132: 384: 29.41
+	At
		1106685 CDPK3_ARATH (103-172): 4.65e-14: 70.6: 22.86		MPK7_ARATH (3-363): 8.55e-132: 383: 29.64
+	At
		1106145 CDPKU_ARATH (87-172): 5.02e-13: 67.6: 29.07		MPK2_ARATH (3-363): 6.43e-132: 384: 31.03
+	At
		1106037 CDPKU_ARATH (87-172): 5.02e-13: 67.6: 29.07		MPK1_ARATH (3-368): 1.74e-131: 382: 31.42
+	At
		483189 CALM4_ARATH (98-171): 7.33e-17: 74.9: 24.32		Y1461_ARATH (19-324): 5.34e-71: 233: 45.83
+	At
		188369 CML8_ARATH (90-171): 3.04e-12: 62.8: 20.73		Y1461_ARATH (19-324): 5.34e-71: 233: 45.83
+	At
		976707 CALM6_ARATH (32-93): 7.82e-12: 61.7: 31.82		Y1461_ARATH (19-324): 5.34e-71: 233: 45.83
+	At
		886647 CALM7_ARATH (20-93): 8.05e-09: 53.3: 24.36		Y1461_ARATH (19-324): 5.34e-71: 233: 45.83