HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: KCD12 (Q96CX2)
BTB/POZ domain-containing protein KCTD12 (Pfetin) (Predominantly fetal expressed T1 domain)
Gene: KCTD12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36398662
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 736 Hs			1 325
+	Hs
		159647 DVL2_HUMAN (1-736): 0: 545: 100.00		BACD2_HUMAN (11-269): 7.36e-71: 224: 22.18
+	Hs
		1371435 DVL3_HUMAN (11-736): 5.52e-160: 481: 64.77		BACD3_HUMAN (1-267): 3.25e-74: 232: 21.09
+	Hs
		1371408 DVL3_HUMAN (11-736): 5.52e-160: 481: 64.77		KCTD7_HUMAN (1-139): 2.42e-40: 144: 26.62
+	Mm
		1223571 DLG4_MOUSE (112-707): 3.19e-72: 251: 16.27		KCD12_MOUSE (1-325): 7.34e-129: 372: 96.02
+	Mm
		1283513 DLG1_MOUSE (94-707): 2.4e-83: 285: 15.77		BACD1_MOUSE (1-265): 1.81e-73: 231: 21.21
+	Hs
		1228956 RIMS1_HUMAN (92-722): 1.81e-46: 181: 14.15		KCD16_HUMAN (20-325): 2.96e-106: 318: 53.57
+	Mm
		999792 DLG3_MOUSE (80-706): 1.45e-71: 252: 15.33		BACD1_MOUSE (1-265): 1.81e-73: 231: 21.21
+	Mm
		1223613 DLG4_MOUSE (112-707): 3.19e-72: 251: 16.27		BACD1_MOUSE (1-265): 1.81e-73: 231: 21.21
+	Ce
		115040 H2KZ17_CAEEL (14-602): 9.22e-103: 332: 34.98		H2KY83_CAEEL (36-210): 1.2e-42: 147: 22.03
+	Ce
		115353 H2KZ17_CAEEL (14-602): 9.22e-103: 332: 34.98		Q18776_CAEEL (4-139): 4.19e-40: 143: 31.62
+	Ce
		115343 H2KZ17_CAEEL (14-602): 9.22e-103: 332: 34.98		P91563_CAEEL (32-150): 6.84e-40: 141: 24.37
+	Mm
		1296193 DLG2_MOUSE (93-707): 5.93e-61: 221: 14.15		BACD1_MOUSE (1-265): 1.81e-73: 231: 21.21
+	Hs
		1006055 DLG4_HUMAN (112-707): 3.91e-72: 250: 15.95		KCNA1_HUMAN (1-222): 6.53e-51: 177: 15.49
+	Mm
		595024 DLG4_MOUSE (112-707): 3.19e-72: 251: 16.27		KCNA1_MOUSE (1-222): 1.02e-49: 174: 15.49
+	Hs
		595035 DLG4_HUMAN (112-707): 3.91e-72: 250: 15.95		KCNA2_HUMAN (1-238): 9.39e-49: 171: 15.66
+	Mm
		990946 DLG4_MOUSE (112-707): 3.19e-72: 251: 16.27		KCNA2_MOUSE (1-238): 7.37e-48: 169: 15.66
+	Hs
		1006112 DLG4_HUMAN (112-707): 3.91e-72: 250: 15.95		KCND2_HUMAN (3-172): 5.45e-46: 166: 19.44
+	Hs
		1130013 DLG3_HUMAN (80-706): 1.07e-73: 257: 14.63		KCTD2_HUMAN (36-129): 2.2e-33: 125: 37.90
+	Hs
		936498 AFAD_HUMAN (256-712): 5.05e-48: 186: 21.41		KCTD3_HUMAN (15-215): 6.69e-42: 156: 25.12
+	Hs
		936406 AFAD_HUMAN (256-712): 5.05e-48: 186: 21.41		KCNB2_HUMAN (3-184): 2.17e-41: 155: 15.46