HitPredict

Interactor 1: NHRF1 (O14745)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
Gene: NHERF1

Interactor 2: P2RY2 (P41231)
P2Y purinoceptor 2 (P2Y2) (ATP receptor) (P2U purinoceptor 1) (P2U1) (P2U receptor 1) (Purinergic receptor)
Gene: P2RY2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	9671706
Identification Methods	filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 358 Hs			1 377
+	Hs
		162806 NHRF1_HUMAN (1-358): 9.87e-82: 254: 100.00		P2RY1_HUMAN (1-336): 1.62e-75: 240: 34.31
+	Hs
		162767 NHRF1_HUMAN (1-358): 9.87e-82: 254: 100.00		ADRB2_HUMAN (2-351): 7.1e-75: 239: 12.70
+	Hs
		162799 NHRF1_HUMAN (1-358): 9.87e-82: 254: 100.00		OPRK_HUMAN (1-335): 7.57e-72: 230: 24.13
+	Hs
		669169 SNTB1_HUMAN (5-347): 1.02e-40: 152: 16.07		ADA1D_HUMAN (36-374): 2.78e-68: 226: 16.07
+	Hs
		907014 NHRF2_HUMAN (4-187): 1.29e-21: 95.9: 36.96		CCR6_HUMAN (16-317): 6.45e-88: 271: 24.27
+	Hs
		669170 SCRIB_HUMAN (7-337): 2.53e-29: 121: 19.83		ADA1D_HUMAN (36-374): 2.78e-68: 226: 16.07
+	Hs
		770719 NHRF3_HUMAN (1-120): 5.05e-21: 95.9: 34.96		SSR5_HUMAN (2-364): 1.26e-79: 250: 27.20
+	Hs
		458410 NHRF2_HUMAN (4-187): 1.29e-21: 95.9: 36.96		ADRB2_HUMAN (2-351): 7.1e-75: 239: 12.70
+	Hs
		1101507 NHRF3_HUMAN (1-120): 5.05e-21: 95.9: 34.96		GPR17_HUMAN (15-346): 3.12e-74: 236: 30.15
+	Mm
		616491 MAGI3_MOUSE (17-285): 1.39e-17: 86.2: 17.06		ADRB2_MOUSE (3-370): 9.98e-77: 244: 14.54
+	Hs
		458428 MAGI3_HUMAN (17-285): 1.89e-18: 88.9: 16.39		ADRB2_HUMAN (2-351): 7.1e-75: 239: 12.70
+	Rn
		723590 DLG4_RAT (88-235): 2.09e-13: 73.5: 19.36		SSR4_RAT (1-370): 6.67e-78: 246: 24.13
+	Rn
		528537 DLG4_RAT (88-235): 2.09e-13: 73.5: 19.36		ADRB2_RAT (4-370): 1.38e-74: 239: 15.08
+	Rn
		723863 DLG4_RAT (88-235): 2.09e-13: 73.5: 19.36		P2RY1_RAT (1-336): 1.1e-73: 235: 34.60
+	Hs
		1118455 SNTB1_HUMAN (5-347): 1.02e-40: 152: 16.07		CLTR2_HUMAN (29-311): 5.2e-40: 146: 33.33
+	Hs
		1368722 DLG3_HUMAN (14-292): 1.13e-29: 122: 14.24		CLTR2_HUMAN (29-311): 5.2e-40: 146: 33.33
+	Hs
		1122356 SCRIB_HUMAN (7-337): 2.53e-29: 121: 19.83		CLTR2_HUMAN (29-311): 5.2e-40: 146: 33.33
+	Hs
		1212241 NHRF3_HUMAN (1-120): 5.05e-21: 95.9: 34.96		CLTR2_HUMAN (29-311): 5.2e-40: 146: 33.33
+	Hs
		1401120 MAGI1_HUMAN (3-318): 2.73e-18: 88.5: 15.34		CLTR2_HUMAN (29-311): 5.2e-40: 146: 33.33
+	Hs
		299798 MPDZ_HUMAN (1-187): 1.97e-14: 77: 22.45		CLTR2_HUMAN (29-311): 5.2e-40: 146: 33.33