Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS
Interactor 2: ZFY16 (Q7Z3T8)
Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein)
Gene: ZFYVE16
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 34761192 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FYVE~FYVE, FYVE~VHS |
| Common GO terms | GO:0005769 - early endosome GO:0005829 - cytosol GO:0006622 - protein targeting to lysosome GO:0007165 - signal transduction GO:0008270 - zinc ion binding and 2 others more... |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
