Interactor 1: PPM1D (O15297)
Protein phosphatase 1D (EC 3.1.3.16) (Protein phosphatase 2C isoform delta) (PP2C-delta) (Protein phosphatase magnesium-dependent 1 delta) (p53-induced protein phosphatase 1)
Gene: PPM1D

Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.646

The method score is based on:

Property Details
Experiments 28027003, 32807901, 33503543
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol
GO:0008285 - negative regulation of cell population proliferation
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 605
Hs

1 393
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024