Protein: PLXD1
Plexin-D1

Gene: PLXD1, PLXND1
Organism: Homo sapiens
Interactions: 37
UniProt ID: Q9Y4D7

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001822 - kidney development
GO:0002116 - semaphorin receptor complex
GO:0003151 - outflow tract morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

175533

SEM3E
Semaphorin-3E

1

17

Small-scale

0.692

High

1432876

SEM4A
Semaphorin-4A

1

18

Small-scale

0.692

High

164482

NRP1
Neuropilin-1

1

20

Small-scale

0.618

High

778118

VGFR2
Vascular endothelial growth factor receptor 2

1

16

Small-scale

0.618

High

1491390

PLXD1
Plexin-D1

1

20

Small-scale

0.618

High

480941

LEG1
Galectin-1

2

7

High-throughput

0.601

High

262345

SCN2B
Sodium channel regulatory subunit beta-2

1

5

High-throughput

0.575

High

1116337

PTC1
Protein patched homolog 1

1

10

High-throughput

0.536

High

1460874

FBX2
F-box only protein 2

1

17

High-throughput

0.536

High

1293941

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

6

High-throughput

0.514

High

1462483

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

5

Small-scale

0.508

High

548154

PSPC
Surfactant protein C

1

8

High-throughput

0.489

High

880080

DNSL1
Deoxyribonuclease-1-like 1

1

5

High-throughput

0.489

High

1359283

CA054
Uncharacterized protein C1orf54

1

9

High-throughput

0.489

High

219005

TGON2
Trans-Golgi network integral membrane protein 2

1

17

High-throughput

0.479

High

243387

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

774724

BASI
Basigin

1

10

High-throughput

0.479

High

783183

ARL3
ADP-ribosylation factor-like protein 3

1

7

High-throughput

0.479

High

522034

H14
Histone H1.4

1

1

High-throughput

0.470

High

652608

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

5

Small-scale

0.462

High

250176

ADCY9
Adenylate cyclase type 9

1

5

High-throughput

0.445

High

914509

EFNB2
Ephrin-B2

1

1

High-throughput

0.445

High

948971

CD81
CD81 antigen

1

3

High-throughput

0.445

High

1100746

STX3
Syntaxin-3

1

3

High-throughput

0.445

High

1491392

NPTN
Neuroplastin

1

12

High-throughput

0.445

High

158030

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.437

High

450354

ACBP
Acyl-CoA-binding protein

1

1

High-throughput

0.437

High

462728

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

8

High-throughput

0.437

High

1388671

SPDLY
Protein Spindly

1

3

High-throughput

0.437

High

388342

GLPA
Glycophorin-A

1

0

High-throughput

0.426

High

1120521

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.426

High

1390800

S47A1
Multidrug and toxin extrusion protein 1

1

0

High-throughput

0.426

High

1491391

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.426

High

171031

CLGN
Calmegin

1

11

High-throughput

0.407

High

1294872

STX12
Syntaxin-12

1

3

High-throughput

0.407

High

478744

HXB5
Homeobox protein Hox-B5

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025