Interactor 1: SHIP2 (O15357)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (EC 3.1.3.86) (Inositol polyphosphate phosphatase-like protein 1) (INPPL-1) (Protein 51C) (SH2 domain-containing inositol 5'-phosphatase 2) (SH2 domain-containing inositol phosphatase 2) (SHIP-2)
Gene: INPPL1

Interactor 2: M3K13 (O43283)
Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Leucine zipper-bearing kinase) (Mixed lineage kinase) (MLK)
Gene: MAP3K13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 0.80 0.726

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SAM_1, PK_Tyr_Ser-Thr~SH2
Common GO terms -
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1258
Hs

1 966
+ Mm
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Mm
+ Hs

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Last updated: 15 Jul 2024