HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2479 Hs			1 446
+	Hs
		176978 CE290_HUMAN (1-2479): 0: 663: 100.00		DCTN1_HUMAN (75-339): 2.67e-10: 64.7: 10.33
+	Mm
		148301 CE290_MOUSE (1-2452): 0: 633: 87.04		DCTN1_MOUSE (75-339): 2.22e-10: 65.1: 10.33
+	Hs
		1095643 PLEC_HUMAN (2-1203): 2.95e-36: 154: 9.37		CACO2_HUMAN (1-446): 2.19e-63: 213: 100.00
+	Hs
		563008 MYH6_HUMAN (1748-2477): 7.5e-24: 113: 13.13		CACO2_HUMAN (1-446): 2.19e-63: 213: 100.00
+	Hs
		883889 CENPF_HUMAN (343-2474): 3.3e-54: 213: 10.59		CENPE_HUMAN (124-345): 4e-10: 64.4: 21.34
+	Hs
		1035504 CENPE_HUMAN (5-1551): 1.56e-52: 207: 10.96		DCTN1_HUMAN (75-339): 2.67e-10: 64.7: 10.33
+	Hs
		1035499 CENPE_HUMAN (5-1551): 1.56e-52: 207: 10.96		CENPE_HUMAN (124-345): 4e-10: 64.4: 21.34
+	Hs
		563036 MYH6_HUMAN (1748-2477): 7.5e-24: 113: 13.13		CACO1_HUMAN (23-434): 2.24e-32: 132: 19.36
+	Hs
		1143214 PLEC_HUMAN (2-1203): 2.95e-36: 154: 9.37		MY18A_HUMAN (108-352): 6.96e-11: 66.7: 14.44
+	Hs
		1143138 PLEC_HUMAN (2-1203): 2.95e-36: 154: 9.37		GRDN_HUMAN (135-355): 6.22e-09: 60.6: 21.34
+	Hs
		772814 PLEC_HUMAN (2-1203): 2.95e-36: 154: 9.37		MYH9_HUMAN (144-345): 7.97e-09: 60.2: 15.05
+	Mm
		1037835 MYH1_MOUSE (1501-2477): 1.16e-34: 148: 11.95		MYH6_MOUSE (80-439): 1.42e-09: 62.4: 11.83
+	Hs
		1191475 CP250_HUMAN (6-974): 1.05e-31: 139: 10.65		GRDN_HUMAN (135-355): 6.22e-09: 60.6: 21.34
+	Hs
		772991 CP250_HUMAN (6-974): 1.05e-31: 139: 10.65		MYH9_HUMAN (144-345): 7.97e-09: 60.2: 15.05
+	Hs
		562992 MYH6_HUMAN (1748-2477): 7.5e-24: 113: 13.13		MYH6_HUMAN (74-439): 4.32e-10: 64.4: 11.26
+	Hs
		535921 MYH6_HUMAN (1748-2477): 7.5e-24: 113: 13.13		MYH3_HUMAN (75-437): 1e-09: 63.2: 9.34
+	Hs
		1123876 MACF1_HUMAN (859-2479): 1.53e-20: 102: 9.70		DCTN1_HUMAN (75-339): 2.67e-10: 64.7: 10.33
+	Mm
		563088 MYH8_MOUSE (1881-2476): 1.01e-20: 102: 11.22		MYH6_MOUSE (80-439): 1.42e-09: 62.4: 11.83
+	Hs
		116295 H3BPE1_HUMAN (859-2479): 1.53e-20: 102: 9.70		MYH9_HUMAN (144-345): 7.97e-09: 60.2: 15.05
+	Hs
		773085 MACF1_HUMAN (859-2479): 1.53e-20: 102: 9.70		MYH9_HUMAN (144-345): 7.97e-09: 60.2: 15.05