HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: MTG16 (O75081)
Protein CBFA2T3 (MTG8-related protein 2) (Myeloid translocation gene on chromosome 16 protein) (hMTG16) (Zinc finger MYND domain-containing protein 4)
Gene: CBFA2T3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	12242670, 11533236
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 653
+	Hs
		253976 HDAC1_HUMAN (3-385): 0: 588: 62.92		MTG16_HUMAN (1-653): 0: 1003: 100.00
+	Hs
		253997 HDAC2_HUMAN (3-422): 0: 580: 58.63		MTG16_HUMAN (1-653): 0: 1003: 100.00
+	Hs
		177273 HDAC3_HUMAN (1-428): 0: 600: 100.00		MTG8_HUMAN (54-653): 0: 846: 69.67
+	Hs
		177133 HDAC3_HUMAN (1-428): 0: 600: 100.00		MTG8R_HUMAN (53-641): 0: 841: 57.64
+	Hs
		987411 HDAC1_HUMAN (3-385): 0: 588: 62.92		MTG8_HUMAN (54-653): 0: 846: 69.67
+	Hs
		987448 HDAC2_HUMAN (3-422): 0: 580: 58.63		MTG8_HUMAN (54-653): 0: 846: 69.67
+	Hs
		254003 HDAC8_HUMAN (6-367): 8.28e-143: 414: 41.71		MTG16_HUMAN (1-653): 0: 1003: 100.00
+	Hs
		254014 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		MTG16_HUMAN (1-653): 0: 1003: 100.00
+	Hs
		987465 HDAC8_HUMAN (6-367): 8.28e-143: 414: 41.71		MTG8_HUMAN (54-653): 0: 846: 69.67