HitPredict

Interactor 1: EPHB6 (O15197)
Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6)
Gene: EPHB6

Interactor 2: UNC5B (Q8IZJ1)
Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1) (p53RDL1)
Gene: UNC5B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	I-set~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1021 Hs			1 945
+	Hs
		710861 EPHB2_HUMAN (33-1020): 0: 1118: 45.97		UNC5B_HUMAN (1-945): 0: 946: 100.00
+	Hs
		932098 EPHA4_HUMAN (14-1021): 0: 1111: 39.47		UNC5B_HUMAN (1-945): 0: 946: 100.00
+	Hs
		1147372 EPHA7_HUMAN (16-1013): 0: 1104: 39.67		UNC5B_HUMAN (1-945): 0: 946: 100.00
+	Hs
		931868 EPHA5_HUMAN (18-1021): 0: 1093: 38.07		UNC5B_HUMAN (1-945): 0: 946: 100.00
+	Hs
		710730 EPHA8_HUMAN (33-1017): 0: 1024: 38.33		UNC5B_HUMAN (1-945): 0: 946: 100.00
+	Hs
		710355 EPHA2_HUMAN (31-1017): 0: 988: 37.25		UNC5B_HUMAN (1-945): 0: 946: 100.00
+	Hs
		328779 EPHA2_HUMAN (31-1017): 0: 988: 37.25		UNC5C_HUMAN (34-944): 0: 850: 63.78
+	Hs
		439783 INSR_HUMAN (421-949): 1.01e-134: 442: 25.76		UNC5B_HUMAN (1-945): 0: 946: 100.00
+	Hs
		710600 EPHA2_HUMAN (31-1017): 0: 988: 37.25		ROBO1_HUMAN (2-291): 4.46e-42: 169: 18.18
+	Hs
		710503 EPHA2_HUMAN (31-1017): 0: 988: 37.25		ROBO2_HUMAN (2-244): 1.37e-38: 158: 16.47
+	Hs
		465575 IGF1R_HUMAN (385-555): 3.27e-11: 69.7: 22.41		UNC5B_HUMAN (1-945): 0: 946: 100.00
+	Hs
		439776 INSR_HUMAN (421-949): 1.01e-134: 442: 25.76		UN5CL_HUMAN (492-931): 2.43e-116: 367: 23.73
+	Hs
		720200 UFO_HUMAN (269-967): 1.13e-144: 456: 21.45		ZO1_HUMAN (413-656): 5.95e-48: 188: 23.70
+	Ce
		109605 VAB1_CAEEL (643-997): 1.58e-105: 357: 34.70		SAX3_CAEEL (2-246): 6.55e-22: 104: 10.94
+	Hs
		465567 IGF1R_HUMAN (385-555): 3.27e-11: 69.7: 22.41		UN5CL_HUMAN (492-931): 2.43e-116: 367: 23.73