HitPredict

Interactor 1: RAB6 (O18334)
Ras-related protein Rab6 (Protein warthog)
Gene: RAB6

Interactor 2: EVI5 (Q9VYY9)
Ecotropic viral integration site 5 ortholog
Gene: EVI5

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.821

Property	Details
Experiments	25453831, 15710747
Identification Methods	affinity chromatography technology, two hybrid, two hybrid fragment pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 208 Dm			1 807
+	Hs
		955922 RAB8A_HUMAN (10-203): 8.37e-88: 258: 40.51		TBC8B_HUMAN (105-657): 1.56e-81: 285: 18.68
+	Dm
		197387 O18335_DROME (1-207): 6.04e-83: 247: 30.37		EVI5_DROME (1-807): 7.06e-78: 269: 100.00
+	Sc
		918923 YPT6_YEAST (7-183): 3.31e-82: 244: 69.27		GYP2_YEAST (74-764): 3.68e-77: 270: 16.71
+	Hs
		1155376 RB11B_HUMAN (1-207): 1.33e-85: 253: 30.56		EVI5L_HUMAN (3-767): 7.79e-66: 236: 36.90
+	Hs
		976478 RB11A_HUMAN (1-207): 9.23e-86: 253: 31.31		EVI5L_HUMAN (3-767): 7.79e-66: 236: 36.90
+	Hs
		247484 RB11A_HUMAN (1-207): 9.23e-86: 253: 31.31		TBC12_HUMAN (7-361): 6.68e-65: 233: 21.13
+	Hs
		976376 RB11A_HUMAN (1-207): 9.23e-86: 253: 31.31		TBCD1_HUMAN (8-460): 2.07e-63: 233: 23.79
+	Hs
		955943 RAB8A_HUMAN (10-203): 8.37e-88: 258: 40.51		TBC9B_HUMAN (5-329): 3.99e-57: 214: 21.30
+	Hs
		1155398 RB11B_HUMAN (1-207): 1.33e-85: 253: 30.56		TBC14_HUMAN (6-375): 1.58e-59: 216: 20.00
+	Hs
		976628 RB11A_HUMAN (1-207): 9.23e-86: 253: 31.31		TBC14_HUMAN (6-375): 1.58e-59: 216: 20.00
+	Hs
		900986 RAB5C_HUMAN (7-188): 3.49e-51: 166: 41.12		SGSM3_HUMAN (21-496): 4.42e-65: 233: 17.58
+	Hs
		631408 RAB5A_HUMAN (7-174): 1.11e-48: 159: 44.64		SGSM3_HUMAN (21-496): 4.42e-65: 233: 17.58
+	Hs
		956601 RAB5B_HUMAN (12-174): 3.99e-47: 155: 44.79		SGSM3_HUMAN (21-496): 4.42e-65: 233: 17.58
+	Hs
		1295418 RAB43_HUMAN (13-173): 2.04e-45: 151: 46.30		EVI5L_HUMAN (3-767): 7.79e-66: 236: 36.90
+	Hs
		76310 RAB5C_HUMAN (7-188): 3.49e-51: 166: 41.12		B4DMS2_HUMAN (105-496): 9.8e-58: 209: 19.30
+	Hs
		248977 RB11A_HUMAN (1-207): 9.23e-86: 253: 31.31		EVI5_HUMAN (294-770): 1.37e-15: 83.1: 17.01
+	Hs
		248986 RB11B_HUMAN (1-207): 1.33e-85: 253: 30.56		EVI5_HUMAN (294-770): 1.37e-15: 83.1: 17.01
+	Hs
		631715 RAB6A_HUMAN (1-208): 4.96e-86: 254: 87.56		RBGP1_HUMAN (547-803): 7.97e-09: 61.5: 12.21
+	Hs
		976687 RB11A_HUMAN (1-207): 9.23e-86: 253: 31.31		RBGP1_HUMAN (547-803): 7.97e-09: 61.5: 12.21