Protein: SGSM3
Small G protein signaling modulator 3 (Merlin-associated protein) (RUN and TBC1 domain-containing protein 3) (Rab-GTPase-activating protein-like protein) (RabGAPLP)

Gene: SGSM3
Organism: Homo sapiens
Interactions: 21
UniProt ID: Q96HU1

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0005921 - gap junction
GO:0031267 - small GTPase binding
GO:0032483 - regulation of Rab protein signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

900986

RAB5C
Ras-related protein Rab-5C

2

17

Small-scale

0.757

High

631408

RAB5A
Ras-related protein Rab-5A

1

14

Small-scale

0.621

High

956601

RAB5B
Ras-related protein Rab-5B

1

17

Small-scale

0.621

High

412435

NTRK1
High affinity nerve growth factor receptor

1

20

Small-scale

0.618

High

1356976

PDC6I
Programmed cell death 6-interacting protein

2

0

Small-scale

0.593

High

767303

MERL
Merlin

1

2

Small-scale

0.573

High

1387186

RB39B
Ras-related protein Rab-39B

1

15

Small-scale

0.555

High

486602

TACD2
Tumor-associated calcium signal transducer 2

1

3

High-throughput

0.536

High

249186

DSCAM
Cell adhesion molecule DSCAM

1

1

High-throughput

0.494

High

1153424

CD226
CD226 antigen

1

6

High-throughput

0.489

High

1393557

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

842486

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.486

High

339824

KLF8
Krueppel-like factor 8

1

2

High-throughput

0.479

High

791630

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

1393556

XPO7
Exportin-7

1

4

High-throughput

0.479

High

212470

SPIT2
Kunitz-type protease inhibitor 2

1

5

High-throughput

0.407

High

1335151

LEMD2
LEM domain-containing protein 2

2

0

High-throughput

0.319

High

726818

FMO3
Flavin-containing monooxygenase 3

2

0

High-throughput

0.316

High

380122

HLAB
HLA class I histocompatibility antigen, B alpha chain

2

0

High-throughput

0.288

High

630182

ACM3
Muscarinic acetylcholine receptor M3

1

0

High-throughput

0.282

High

139288

UPK2
Uroplakin-2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025