HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: CRIM1 (Q9NZV1)
Cysteine-rich motor neuron 1 protein (CRIM-1) (Cysteine-rich repeat-containing protein S52) [Cleaved into: Processed cysteine-rich motor neuron 1 protein]
Gene: CRIM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1036
+	Hs
		436546 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		CRIM1_HUMAN (1-1036): 1.02e-144: 461: 100.00
+	Hs
		951412 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		CRIM1_HUMAN (1-1036): 1.02e-144: 461: 100.00
+	Hs
		894525 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		CRIM1_HUMAN (1-1036): 1.02e-144: 461: 100.00
+	Hs
		900403 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		NOTC2_HUMAN (10-633): 5.55e-20: 98.6: 8.55
+	Hs
		925219 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		NOTC2_HUMAN (10-633): 5.55e-20: 98.6: 8.55
+	Hs
		436267 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		NOTC2_HUMAN (10-633): 5.55e-20: 98.6: 8.55
+	Hs
		901003 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		TEN3_HUMAN (714-923): 5.06e-18: 92.5: 11.98
+	Hs
		950942 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		NOTC2_HUMAN (10-633): 5.55e-20: 98.6: 8.55
+	Hs
		893926 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		NOTC2_HUMAN (10-633): 5.55e-20: 98.6: 8.55
+	Hs
		804189 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		NOTC1_HUMAN (3-449): 1.8e-13: 77.4: 11.61
+	Hs
		804195 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		NOTC1_HUMAN (3-449): 1.8e-13: 77.4: 11.61
+	Hs
		380909 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		VWF_HUMAN (187-665): 7.32e-13: 75.3: 18.60
+	Hs
		436195 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		NOTC1_HUMAN (3-449): 1.8e-13: 77.4: 11.61
+	Hs
		804203 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		NOTC1_HUMAN (3-449): 1.8e-13: 77.4: 11.61
+	Hs
		804187 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		NOTC1_HUMAN (3-449): 1.8e-13: 77.4: 11.61
+	Hs
		925184 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		JAG1_HUMAN (13-325): 1.71e-10: 67.4: 11.18
+	Hs
		436252 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		JAG1_HUMAN (13-325): 1.71e-10: 67.4: 11.18
+	Hs
		944117 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		JAG1_HUMAN (13-325): 1.71e-10: 67.4: 11.18
+	Hs
		951084 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		TEN4_HUMAN (745-907): 1.55e-09: 64.7: 11.15
+	Hs
		894276 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		PXDN_HUMAN (407-456): 3.26e-09: 63.3: 43.14