HitPredict

Interactor 1: NEB2 (O35274)
Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130)
Gene: Ppp1r9b

Interactor 2: KCC2B (P08413)
Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)
Gene: Camk2b

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20124353
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0014069 - postsynaptic density GO:0030425 - dendrite GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 817 Rn			1 542
+	Mm
		704222 NEB2_MOUSE (1-817): 5.32e-115: 370: 98.90		KCC2B_MOUSE (1-542): 0: 630: 99.82
+	Rn
		204569 NEB2_RAT (1-817): 3.36e-116: 373: 100.00		KCC2G_RAT (1-542): 0: 587: 83.21
+	Mm
		1247164 NEB2_MOUSE (1-817): 5.32e-115: 370: 98.90		KCC2G_MOUSE (1-542): 0: 589: 81.07
+	Rn
		204571 NEB2_RAT (1-817): 3.36e-116: 373: 100.00		KCC2D_RAT (1-542): 0: 578: 79.52
+	Mm
		1244501 NEB2_MOUSE (1-817): 5.32e-115: 370: 98.90		KCC2D_MOUSE (1-542): 8.71e-168: 486: 64.76
+	Rn
		204568 NEB2_RAT (1-817): 3.36e-116: 373: 100.00		KCC2A_RAT (3-538): 3.28e-163: 474: 64.37
+	Mm
		548958 NEB2_MOUSE (1-817): 5.32e-115: 370: 98.90		KCC2A_MOUSE (3-538): 3.28e-163: 474: 64.37
+	Mm
		704219 DLG4_MOUSE (444-624): 4.16e-24: 110: 18.79		KCC2B_MOUSE (1-542): 0: 630: 99.82
+	Rn
		540144 LRRC7_RAT (5-586): 2.4e-41: 166: 14.04		KCC2A_RAT (3-538): 3.28e-163: 474: 64.37
+	Rn
		540169 DLG1_RAT (64-713): 2.37e-38: 155: 12.54		KCC2A_RAT (3-538): 3.28e-163: 474: 64.37
+	Hs
		1091600 DLG1_HUMAN (64-803): 5.99e-38: 154: 11.08		KCC2A_HUMAN (3-538): 3.7e-163: 474: 64.37
+	Rn
		540173 DLG3_RAT (26-691): 9.98e-32: 135: 12.13		KCC2A_RAT (3-538): 3.28e-163: 474: 64.37
+	Hs
		1368733 DLG3_HUMAN (356-691): 7.58e-31: 132: 12.04		KCC2A_HUMAN (3-538): 3.7e-163: 474: 64.37
+	Mm
		548952 DLG4_MOUSE (444-624): 4.16e-24: 110: 18.79		KCC2A_MOUSE (3-538): 3.28e-163: 474: 64.37
+	Hs
		114565 H0YKB7_HUMAN (277-650): 2.3e-42: 162: 16.88		KCC1A_HUMAN (9-338): 1.76e-140: 411: 38.49
+	Hs
		168736 ERBIN_HUMAN (14-583): 6.6e-43: 170: 13.46		CSKP_HUMAN (10-308): 5.81e-84: 281: 46.73
+	Mm
		267274 DLG1_MOUSE (64-803): 1.28e-38: 156: 11.00		CSKP_MOUSE (10-308): 5.87e-84: 281: 46.73
+	Rn
		1224257 DLG1_RAT (64-713): 2.37e-38: 155: 12.54		CSKP_RAT (10-308): 4.49e-84: 281: 46.73
+	Hs
		168680 DLG1_HUMAN (64-803): 5.99e-38: 154: 11.08		CSKP_HUMAN (10-308): 5.81e-84: 281: 46.73
+	Hs
		168730 DLG3_HUMAN (356-691): 7.58e-31: 132: 12.04		CSKP_HUMAN (10-308): 5.81e-84: 281: 46.73