HitPredict

Interactor 1: RING1 (O35730)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Transcription repressor Ring1A)
Gene: RING1

Interactor 2: UBP7 (Q6A4J8)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (mHAUSP) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: Usp7

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36772830
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 406 Mm			1 1103
+	Hs
		1055836 RING1_HUMAN (1-406): 1.05e-111: 335: 96.55		UBP7_HUMAN (3-1103): 0: 1238: 98.91
+	Mm
		1230577 RING2_MOUSE (8-406): 2.2e-98: 298: 54.25		UBP7_MOUSE (1-1103): 0: 1243: 100.00
+	Hs
		1371630 RING2_HUMAN (8-406): 3.36e-98: 298: 54.25		UBP7_HUMAN (3-1103): 0: 1238: 98.91
+	Hs
		766108 PCGF2_HUMAN (31-378): 9.31e-64: 209: 16.67		UBP7_HUMAN (3-1103): 0: 1238: 98.91
+	Hs
		765771 BMI1_HUMAN (31-370): 4.29e-51: 176: 15.07		UBP7_HUMAN (3-1103): 0: 1238: 98.91
+	Mm
		1230469 PCGF3_MOUSE (34-273): 1.34e-39: 143: 16.80		UBP7_MOUSE (1-1103): 0: 1243: 100.00
+	Mm
		1230524 PCGF1_MOUSE (25-130): 1.17e-38: 141: 24.77		UBP7_MOUSE (1-1103): 0: 1243: 100.00
+	Mm
		1230570 PCGF6_MOUSE (31-157): 1.54e-36: 138: 23.08		UBP7_MOUSE (1-1103): 0: 1243: 100.00
+	Hs
		1185932 PCGF3_HUMAN (34-273): 3.4e-39: 142: 16.33		UBP7_HUMAN (3-1103): 0: 1238: 98.91
+	Hs
		1371646 PCGF1_HUMAN (25-130): 8.97e-39: 141: 24.77		UBP7_HUMAN (3-1103): 0: 1238: 98.91
+	Hs
		1315292 TRI22_HUMAN (41-343): 1.69e-34: 135: 10.68		UBP7_HUMAN (3-1103): 0: 1238: 98.91
+	Mm
		1190380 PCGF5_MOUSE (31-169): 3.29e-33: 126: 21.13		UBP7_MOUSE (1-1103): 0: 1243: 100.00
+	Hs
		1371658 PCGF6_HUMAN (29-161): 3.83e-33: 129: 22.06		UBP7_HUMAN (3-1103): 0: 1238: 98.91
+	Hs
		766016 BMI1_HUMAN (31-370): 4.29e-51: 176: 15.07		UBP22_HUMAN (45-522): 5.96e-115: 368: 16.49
+	Hs
		1257941 PCGF1_HUMAN (25-130): 8.97e-39: 141: 24.77		UBP34_HUMAN (126-644): 4.11e-96: 339: 19.51
+	Hs
		1412817 PCGF1_HUMAN (25-130): 8.97e-39: 141: 24.77		UBP42_HUMAN (204-556): 3.39e-96: 335: 24.05
+	Hs
		1371519 PCGF1_HUMAN (25-130): 8.97e-39: 141: 24.77		USP9X_HUMAN (209-555): 1.63e-94: 334: 25.11