HitPredict

Interactor 1: MTLR (O43193)
Motilin receptor (G-protein coupled receptor 38)
Gene: MLNR

Interactor 2: TNPO3 (Q9Y5L0)
Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR)
Gene: TNPO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 923
+	Hs
		1101716 GPR17_HUMAN (4-376): 3.43e-67: 219: 20.94		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		770936 OPRM_HUMAN (5-405): 1.94e-62: 208: 20.30		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		771273 APJ_HUMAN (40-403): 1.13e-62: 208: 21.68		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		172773 GPR17_HUMAN (4-376): 3.43e-67: 219: 20.94		XPO1_HUMAN (3-920): 6.79e-151: 475: 12.37
+	Hs
		172513 APJ_HUMAN (40-403): 1.13e-62: 208: 21.68		XPO1_HUMAN (3-920): 6.79e-151: 475: 12.37
+	Hs
		318134 GPR17_HUMAN (4-376): 3.43e-67: 219: 20.94		IPO13_HUMAN (5-923): 2.11e-143: 452: 21.02
+	Hs
		318120 OPRM_HUMAN (5-405): 1.94e-62: 208: 20.30		IPO13_HUMAN (5-923): 2.11e-143: 452: 21.02
+	Hs
		210377 MTLR_HUMAN (1-412): 6.2e-78: 248: 100.00		IPO7_HUMAN (13-813): 8.67e-101: 340: 11.63
+	Hs
		189070 MTLR_HUMAN (1-412): 6.2e-78: 248: 100.00		IPO8_HUMAN (10-813): 5.23e-89: 307: 9.92
+	Hs
		318150 PKR1_HUMAN (37-315): 2.36e-20: 94: 26.24		IPO13_HUMAN (5-923): 2.11e-143: 452: 21.02
+	Hs
		220905 GPR17_HUMAN (4-376): 3.43e-67: 219: 20.94		XPOT_HUMAN (12-770): 1.77e-93: 318: 15.10
+	Hs
		164568 GPR17_HUMAN (4-376): 3.43e-67: 219: 20.94		TNPO2_HUMAN (68-784): 3.35e-92: 313: 12.26
+	Hs
		189155 GPR17_HUMAN (4-376): 3.43e-67: 219: 20.94		IPO8_HUMAN (10-813): 5.23e-89: 307: 9.92
+	Hs
		189118 APJ_HUMAN (40-403): 1.13e-62: 208: 21.68		IPO8_HUMAN (10-813): 5.23e-89: 307: 9.92
+	Hs
		164529 EDNRB_HUMAN (42-363): 1.61e-20: 94.7: 22.99		TNPO2_HUMAN (68-784): 3.35e-92: 313: 12.26
+	Hs
		1101666 GPR17_HUMAN (4-376): 3.43e-67: 219: 20.94		XPO5_HUMAN (9-614): 3.05e-22: 105: 14.21
+	Hs
		771237 APJ_HUMAN (40-403): 1.13e-62: 208: 21.68		XPO5_HUMAN (9-614): 3.05e-22: 105: 14.21
+	Hs
		458402 ADRB2_HUMAN (1-395): 1.47e-66: 219: 16.27		IMB1_HUMAN (38-691): 1.58e-09: 64.1: 9.56
+	Hs
		665312 EDNRB_HUMAN (42-363): 1.61e-20: 94.7: 22.99		Q4LE60_HUMAN (161-691): 3.1e-11: 69.5: 9.70