Interactor 1: GET3 (O43681)
ATPase GET3 (EC 3.6.-.-) (Arsenical pump-driving ATPase) (Arsenite-stimulated ATPase) (Guided entry of tail-anchored proteins factor 3, ATPase) (Transmembrane domain recognition complex 40 kDa ATPase subunit) (hARSA-I) (hASNA-I)
Gene: GET3

Interactor 2: CAMLG (P49069)
Guided entry of tail-anchored proteins factor CAMLG (Calcium signal-modulating cyclophilin ligand)
Gene: CAMLG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 0.90 0.855

The method score is based on:

Property Details
Experiments 28514442, 32296183, 33961781, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ArsA_ATPase~Get2_like
Common GO terms GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0043529 - GET complex
GO:0045048 - protein insertion into ER membrane
GO:0071816 - tail-anchored membrane protein insertion into ER membrane
Homologous interactions 0

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Last updated: 15 Jul 2024