HitPredict

Interactor 1: SIGL6 (O43699)
Sialic acid-binding Ig-like lectin 6 (Siglec-6) (CD33 antigen-like 1) (CDw327) (Obesity-binding protein 1) (OB-BP1) (CD antigen CD327)
Gene: SIGLEC6

Interactor 2: FHL2 (Q14192)
Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3)
Gene: FHL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.80	0.662

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LIM~V-set
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 453 Hs			1 279
+	Hs
		1050732 TITIN_HUMAN (1-453): 2.52e-09: 62: 8.58		FHL2_HUMAN (1-279): 4.64e-77: 237: 100.00
+	Hs
		1151801 TITIN_HUMAN (1-453): 2.52e-09: 62: 8.58		ABLM2_HUMAN (3-212): 5.24e-45: 162: 20.27
+	Hs
		150606 TITIN_HUMAN (1-453): 2.52e-09: 62: 8.58		ABLM1_HUMAN (91-279): 2.1e-38: 145: 21.61
+	Hs
		581539 VCAM1_HUMAN (105-365): 6.87e-20: 94.4: 19.42		PAXI_HUMAN (187-279): 1.89e-18: 86.9: 23.53
+	Hs
		816266 TITIN_HUMAN (1-453): 2.52e-09: 62: 8.58		LIMS1_HUMAN (3-157): 4.12e-25: 103: 21.80
+	Ce
		107557 UNC89_CAEEL (252-346): 2.2e-11: 68.5: 15.84		G5EFG1_CAEEL (3-150): 1.53e-19: 90.1: 30.67
+	Ce
		136803 UNC89_CAEEL (252-346): 2.2e-11: 68.5: 15.84		Q3S1I9_CAEEL (3-97): 4.03e-14: 72.6: 42.27
+	Hs
		1044559 TITIN_HUMAN (1-453): 2.52e-09: 62: 8.58		FHL1_HUMAN (183-279): 8.68e-11: 63.4: 30.28