Interactor 1: ACTN4 (O43707)
Alpha-actinin-4 (Non-muscle alpha-actinin 4)
Gene: ACTN4

Interactor 2: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 26496610, 22662192
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, CH~EFhand_Ca_insen, CH~Spectrin
Common GO terms GO:0005509 - calcium ion binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
and 4 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 911
Hs

1 1657
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm

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Last updated: 15 Jul 2024